The reduction in mechanical load imparted on the body during spaceflight presents unique physiological challenges. One detrimental and seemingly unavoidable response to microgravity is rapid bone loss. This adaptation is hazardous not only to astronaut health, but to the success of long-duration exploration-class missions. Skeletal adaptation to spaceflight in astronauts...
Space flight results in loss of mass and function in skeletal
muscle. Data from manned flights and animal biosatellites give
evidence of possible changes in neuromuscular interactions.
Components at the neuromuscular junction are a potential site of
action for this space-induced muscle atrophy. We examined the
nicotinic acetylcholine receptor population...