Extreme water levels generating flooding in estuarine and coastal environments are often driven by compound events, where many individual processes such as waves, storm surge, streamflow, and tides coincide. Despite this, extreme water levels are typically modeled in isolated open-coast or estuarine environments, potentially mischaracterizing the true risk of flooding...
We live in an exciting time for biology. Technological advances have made data collection easier and cheaper than we could ever have imagined just 10 years ago. We can now synthesize and analyze large data sets containing genomes, transcriptomes, proteomes, and multivariate phenotypes. At the same time, society's need for...
Objective: To translate a behavioral weight loss intervention for mid-life, low-income women in real world settings.
Design and Methods: In this pragmatic clinical trial, we randomly selected six North Carolina county health departments and trained their current staff to deliver a 16-session evidence-based behavioral weight loss intervention (special intervention, SI)....
Background: Scientists rarely reuse expert knowledge of phylogeny, in spite of years of effort to assemble a great
“Tree of Life” (ToL). A notable exception involves the use of Phylomatic, which provides tools to generate custom
phylogenies from a large, pre-computed, expert phylogeny of plant taxa. This suggests great potential...
Solid and aqueous phase Al species are recognized to affect organic matter (OM) stabilization in forest soils. However, little is known about the dynamics of formation, composition and dissolution of organo-Al hydroxide complexes in microbially-active soil systems, where plant litter is subject to microbial decomposition in close proximity to mineral...
Forest canopy cover presents a major challenge for remote sensing of fractional snow-covered area (ƒSCA). Snow cover is systematically underestimated where satellites sensors cannot penetrate the forest canopy. Current canopy adjustments scale observable ƒSCA with the vegetation fraction, assuming that snow cover distributions are similar between sub-canopy and open locations....
We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae. In this study, we found that the addition of malonate, an inhibitor of succinate dehydrogenase (SDH), decreased toxT transcription in V. cholerae, an observation inconsistent with the previous pattern...
Disease predictive systems are intended to be management aids. With a few exceptions, these systems typically do not have direct sustained use by growers. Rather, their impact is mostly pedagogic and indirect, improving recommendations from farm advisers and shaping management concepts. The degree to which a system is consulted depends...
Background: Osteosarcoma (OSA) is the most common primary bone tumor of dogs and carries a poor prognosis
despite aggressive treatment. An improved understanding of the biology of OSA is critically needed to allow for
development of novel diagnostic, prognostic, and therapeutic tools. The surface-exposed proteome (SEP) of a
cancerous cell...