Utilizing nanocarrier based drug delivery for improving the magnitude of efficacy of chemotherapeutic agents in many diseases has acquired more attention in research applications. It has shown promising results in both preclinical and clinical trials. The Food and Drug Administration (FDA) has approved many of these polymeric carriers, and tens...
In this thesis, we will study certain generalizations of the classical Shannon Sampling Theorem, which allows for the reconstruction of a pi-band-limited, square-integrable function from its samples on the integers. J. R. Higgins provided a generalization where the integers can be perturbed by less than 1/4, which includes nonuniform and...
X-ray computed tomography is a noninvasive imaging modality capable of reconstructing exact density values of 3D objects. Computed tomography machines are deployed across the world to provide doctors with an image that reveals more detail than a standard x-ray image. We investigate algorithms based on exact computed tomography reconstruction formulas...
Two problems involving high-resolution reconstruction from nonuniformly sampled data in x-ray computed tomography are addressed. A technique based on the theorem for sampling on unions of shifted lattices is introduced which exploits the symmetry property in two-dimensional fan beam computed tomography and permits the reconstruction of images with twice the...
The effects of several hormones and inducers of intracellular
messengers on plasminogen activator (PA) production and changes in
embryonic size by cultured bovine embryos were evaluated. Day 8 embryos
were cultured in Ham's F-12 with 1.5 mg/ml bovine serum albumin (BSA)
containing different levels of progesterone (P), estradiol -17fl (E₂),...
TAC is the most commonly used medication in post transplantation maintenance immunosuppression therapy. TAC lipophilicity and its erratic oral absorption especially in the presence of food intake result in great intra- and interpatient pharmacokinetic variations. Complicated dosing and frequent required therapeutic monitoring is thought to be the main cause of...
In the problem of testing the median using a random sample from a
certain distribution, and if no other parametric family is suggested,
the t-test is known to be the optimal procedure when this distribution
is normal. If the sample appears to be non-normal, one has the choice
either to...
Generalizations of the smooth goodness-of-fit test statistics,
the components of Cramer-von Mises type statistics and the
Pearson chi-square statistics are considered for censored samples.
Asymptotic efficiency comparisons are made between these
general goodness-of-fit tests for Weibull and gamma distributions
for certain parametric alternatives in the case of singly censored
samples....
The purpose of this study was to investigate the effect
of an eight-week instructional program, using different
activities and apparatus, upon the balance performance
of hearing-impaired children, ages 6-12. Balance was
measured by the Bruininks-Oseretsky Test of Motor Proficiency
(Subtest 2: Balance) as a pre- and post-test to
determine if...