Index Catalog // ScholarsArchive@OSU

Detection and Identification of Acetaminophen (Tylenol) Metabolites using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS/MS) Analysis

Creator:: Sanchez, Karina M.
Abstract:: Acetaminophen (APAP) is a commonly used analgesic and antipyretic drug that can cause liver injury, liver necrosis, and liver failure. APAP-induced liver failure (AILF) is associated with depletion of glutathione and the increased formation of APAP protein adducts from the toxic NAPQI metabolite. There is a hypothesized detoxifying pathway where...
Resource Type:: Undergraduate Thesis
Full Text:: Stevens, Professor Secondary Mentor - Dr. Armando Alcazar Magana

Effects of Vineyard Managements on Grape and Wine Quality in Response to Grapevine Red Blotch Disease

Creator:: Huang, Ling
Abstract:: Grapevine red blotch virus (GRBV) is a single-stranded DNA virus that causes grapevine red blotch disease (GRBD). Symptoms of GRBD include red discoloring of leaf margins and red veins on the underside of the leaves. GRBD affects the plant's metabolism and photosynthetic pathways, and disrupts carbon translocation and chlorophyll concentrations....
Resource Type:: Dissertation
Full Text:: China. CONTRIBUTION OF AUTHORS Drs. Armando Alcazar Magana and James Osborne were

The Extraction and Analytical Profiling of Bioactive Phospho- and Sphingolipids from Commercial Whey Protein Phospholipid Concentrate

Creator:: Ferraris, Quintin M.
Abstract:: Milk is the first source of nutrition for all mammalian neonates. The complex matrix that constitutes milk has evolved to provide optimal nutrition for the newborn, for each species, respectively. Milk fat, originating in mammary epithelial, forms lipid droplets which are stabilized in the aqueous environment by bioactive polar lipids...
Resource Type:: Dissertation
Full Text:: first manuscript chapter. Dr. Armando Alcazar Magana was involved with the design and writing of the

Comprehensive Analysis of The Brain Metabolome Using Mass Spectrometry in Conjunction with Data Analysis Techniques

Creator:: Khorani, Mona
Abstract:: Metabolomics has recently gained momentum in biomolecule research and complements the genomics and proteomics research space. Metabolomics strives to detect, identify, and quantify all metabolites present in biological samples. In particular, biomolecular analysis using ultra-performance liquid chromatography combined with mass spectrometry (UPLC-MS) has become increasingly important for metabolomic analyses. Similarly,...
Resource Type:: Dissertation
Full Text:: . Armando Alcazar Magana, my mentor and our group’s postdoctoral fellow, for his invaluable guidance and

Method validation of quantitative analysis of oxylipins in human plasma via mass spectrometry

Creator:: Bloom, Madeline B.
Abstract:: Oxylipins are a class of bioactive lipid metabolites derived from polyunsaturated fatty acids (PUFAs) via enzymatic and non-enzymatic pathways. In order to elucidate their overall biological effects, the knowledge of the entire oxylipin profile is needed as oxylipins can have similar or opposing effects in regard to inflammatory events. Their...
Resource Type:: Honors College Thesis

Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Creator:: Paraiso, Ines L.
Abstract:: Obesity is a complex multifactorial disease resulting from excessive energy intake compared to energy expenditure. The excess energy is mostly stored as fat in enlarged adipocytes, but some lipids may infiltrate other organs such as the liver to form ectopic fat. Adipose tissue and ectopic fat produce and secrete a...
Resource Type:: Dissertation
Full Text:: xanthohumol derivative as part of Chapter 5. Armando Alcazar and Cristobal Miranda contributed to experiment

Investigating the Mechanisms for the Effects of Nitrate Treatment on Exercise Performance and Energy Metabolism

Creator:: Keller, Rosa M.
Abstract:: Dietary nitrate (NO3-), consumed primarily from leafy green and root vegetables, lowers blood pressure, improves vascular function and aerobic exercise performance. This performance-enhancing effect of nitrate supplementation is largely attributed to the increased bioavailability of the signaling molecule, nitric oxide (NO). Nitric oxide is a ubiquitous free radical signaling molecule...
Resource Type:: Dissertation
Full Text:: Alcazar Magana, Dr. Ralph Reed, Dr. Val Miranda, Dr. Jae Woo Choi, Lauren Murphy, and Jessica Li

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Creator:: Koluda, Rony
Abstract:: Radiation exposure to the brain can occur from a variety of events, including space missions, nuclear accidents, and clinical treatments. The effects of high dose radiation are well studied, but those of lower dosage are more elusive. Decline of memory and cognition is observed in patients exposed to low dose...
Resource Type:: Masters Thesis
Full Text:: for his feedback and encouragement throughout the whole process. I want to thank Dr. Armando Alcazar

Assessing the Trade-Off Between Sustainability and Resiliency of Reinforced Concrete Alternatives in Corrosive Conditions: An LCA-System Dynamics Approach

Creator:: Moreno Rangel, Erick D.
Abstract:: Concrete has been categorized as a key contributor of CO2 (carbon) emissions into the atmosphere. This is mostly associated with the production of ordinary portland cement (OPC). The concrete and cement industries are pursuing a path to reduce their carbon emissions generally in accordance with the climate change goals outlined...
Resource Type:: Masters Thesis
Full Text:: , Armando Magaña, Logan Scott-Deeter, Chenqiang Liu, Alex Ruiz, Tony de Siqueira, Besrat Eshetu, Nick

Development and implementation of a transkingdom network analysis pipeline to identify drivers of disease

Creator:: Newman, Nolan K.
Abstract:: The gut microbiome has been previously implemented in a number of diseases. Of note is its substantial role in metabolic syndrome, which encapsulates a group of conditions that increase the risk of cardiovascular disease, type 2 diabetes, and stroke. Understanding the causal relationships between the gut microbiome and host processes...
Resource Type:: Dissertation
Full Text:: the manuscript. Dr. Armando Magana, Kaito Hioki, Amanda Bruce, Jacob Pederson, Dr. Zhipeng Li, Dr

ScholarsArchive@OSU

Detection and Identification of Acetaminophen (Tylenol) Metabolites using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS/MS) Analysis

Effects of Vineyard Managements on Grape and Wine Quality in Response to Grapevine Red Blotch Disease

The Extraction and Analytical Profiling of Bioactive Phospho- and Sphingolipids from Commercial Whey Protein Phospholipid Concentrate

Comprehensive Analysis of The Brain Metabolome Using Mass Spectrometry in Conjunction with Data Analysis Techniques

Method validation of quantitative analysis of oxylipins in human plasma via mass spectrometry

Characterization of the Mechanisms of Action and Molecular Targets of Hop-derived Flavonoids in the Mitigation of Obesity-related Metabolic Impairments

Investigating the Mechanisms for the Effects of Nitrate Treatment on Exercise Performance and Energy Metabolism

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Assessing the Trade-Off Between Sustainability and Resiliency of Reinforced Concrete Alternatives in Corrosive Conditions: An LCA-System Dynamics Approach

Development and implementation of a transkingdom network analysis pipeline to identify drivers of disease

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