The potential impact of chemical contaminants and conservation practices on amphibians in agricultural landscapes is a key research topic globally. Amphibians represent a common group in many freshwater systems and are currently experiencing worldwide population declines. Global amphibian declines may be attributed to a number of causes, including habitat loss,...
The main objective of this project was to compare on-farm measurement techniques for estimating N-contributions from cover crops using 1) separated species lab tests (a standard experimental method), 2) bulked species lab tests, 3) fresh weight, 4) dry weight and 5) canopy height and density. We also recorded relative weed...
With an ever-growing urban population there is a continued interest in urban agriculture as a viable option to improve access to fresh produce and enhance food security in an increasingly urbanized world. As the primary method of urban agriculture in the United States, community gardens also provide a range of...
Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
Genomic integrity is crucial for the viability and function of a cell. One key pathway that acts to
maintain genomic integrity is DNA mismatch repair (MMR). MMR acts to correct base pair
mismatches hat have escaped proofreading during DNA replication. The process of MMR is
dependent on the protein heterodimer...
DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
DNA mismatch repair (MMR) plays an important role in preserving genomic stability and reducing cancer risk. Environmental exposures to polycyclic aromatic hydrocarbons (PAHs) are believed to contribute significantly to carcinogenesis. PAHs are found in food, air, water and soil and upon bioactivation can form diol epoxides which are electrophilic in...
Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic chemical compounds found in the
environment, largely as a result of partial combustion of organic compounds. PAHs are
present in the atmosphere in populated cities worldwide. Because of the health risks they
create, PAHs are a global health concern. PAHs are introduced into the...
Numerous investigations demonstrate that mantle convective processes such as upwelling affect the surface topography of the overriding plate. The surface expression of mantle flow has been coined ‘transient topography’. Transient topography in the North American plate is thought to result from a mantle thermal anomaly beneath the Yellowstone volcanic center,...
For over 30 years, the Implicit Monte Carlo (IMC) method has been used to
solve challenging problems in thermal radiative transfer. These problems are typically optically thick and di ffusive, as a consequence of the high degree of "pseudo-scattering" introduced to model the absorption and reemission of photons from a...