Sickle cell disease (SCD) is a phenotypically variable disorder of hemoglobin that leads to abnormally shaped and dysfunctional red blood cells. Several studies have attempted to construct early predictive models for SCD, including Miller et al.’s (2000) model which uses easily identifiable predictors in early life. The primary aim of...
Linus Pauling incorporated hemoglobin and a disease of the blood, sickle cell anemia, into many of his researches between the mid-1930s and mid-1970s. In the early 1930s Pauling became interested in organic chemistry and named hemoglobin as one of the first biochemical substances that he planned to analyze. In 1935...
Fanconi's Anemia (FA) is an autosomal recessive chromosomal instability disorder. The
symptoms include congenital abnormalities, defective hematopoiesis (formation of cells
of the blood), and high risk of developing acute myeloid leukemia and solid tumors.
Fanconi researchers have long been puzzled by how Fanconi Anemia (FA) cells, which
are known to...
An anemia of juvenile chinook salmon (Oncorhynchus tshawytscha) is described and stages of development separated by recognizable syndromes. A vitamin E-deficient diet of low rancidity produced a severe microcytic anemia with strong immature red cell response and granulocytosis occurring 2 to 4 weeks before a drop in hemoglobin and hematocrit...
I tested a theoretical model proposing that anemia
favors transmission of blood-borne parasites to vectors
by accelerating the blood-feeding rate. Using Aedes
aegypti, the yellow fever mosquito, initially, I was not
able to confirm this phenomenon either in an artificial
or a live system; anemia did not correlate with blood-feeding...