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Molecular and cellular mechanisms of aromatic hydrocarbon axonopathy

Creator:: Kim, Min-Sun
Abstract:: Hydrocarbon solvents are widely used in the production of paints, adhesives, dyes, polymers, plastics, textiles, printing inks, agricultural products and pharmaceuticals. While the neuropathic potential of aliphatic solvents was shown in the 1970s, little is known about the neuropathic potential of aromatic solvents. The present study examines such solvents, 1,2-diethylbenzene...
Resource Type:: Dissertation
Full Text:: . An aromatic compound is an organic compound that contains one or more benzene or equivalent

Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Creator:: Bailey, Bonnie J.
Abstract:: Reported here is an investigation to determine if azinphos-methyl (AZM), an organophosphate insecticide, adducts to hemoglobin, and if so, whether the hemoglobin adduct could be used as a quantitative marker of occupational AZM exposure. We hypothesized that AZM, or a metabolite of AZM, binds to hemoglobin in erythrocytes forming an...
Resource Type:: Dissertation
Full Text:: reacted with water forms an ester. The X constituent places the compound in 1 of 4 main categories: I. X

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Creator:: Madeen, Erin
Abstract:: The objective of this work is to add to the body of translational data between high dose animal model research and the environmentally relevant human metabolism of the persistent pollutant dibenzo[def,p]chrysene (DBC). We furthered the knowledge of gene/exposure interactions by determining the carcinogenesis risk based on Cyp1b1 genotype following in...
Resource Type:: Dissertation
Full Text:: Aromatic Hydrocarbon, Dibenzo[def,p] Chrysene; Carcinogenesis and Metabolism Abstract approved

Diethylnitrosamine, ethylnitrosourea, and dimethylbenz(a)anthracene DNA binding studies in the rainbow trout

Creator:: Van Winkle, Samina
Abstract:: Dimethylbenz (a) anthracene (EMBA), a carcinogen that requires metabolic activation to produce active metabolites capable of binding to DNA, has been studied in the trout and other fish. Polycyclic aromatic hydrocarbons (PAH) are of importance as they are ubiquitous in the environment and their carcinogenic effects in fish from contaminated...
Resource Type:: Masters Thesis
Full Text:: in the trout and other fish. Polycyclic aromatic hydrocarbons (PAH) are of importance as they are

Growth of lactococci relative to antibiotic and quaternary ammonium compounds

Creator:: Valladao, Marilin
Abstract:: The work presented in this thesis is concerned with the effect of several antibiotics and quaternary ammonium sanitizers upon growth of lactic acid bacteria. Section I reports the purification of beta-lactamase from Lactococcus cremoris PR-108, by ion exchange chromatography, using the chromogenic substrate pyridine-2-azo-p-dimethylaniline (PADAC) as the enzymatic indicator. Section...
Resource Type:: Masters Thesis
Full Text:: thesis is concerned with the effect of several antibiotics and quaternary ammonium sanitizers upon

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Creator:: Norby, Tyler S.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
Resource Type:: Masters Thesis
Full Text:: Aromatic Hydrocarbon Mixture Abstract approved: Lawrence R. Curtis Polycyclic aromatic hydrocarbons

Total exposure profiles of azinphosmethyl and azinphosmethyl-oxon to orchard workers in the Pacific Northwest

Creator:: Moate, Thomas F.
Resource Type:: Masters Thesis
Full Text:: been reported up to 30 times that of the parent compound (Knaak, 1980). Worker poisonings by OP

Development of a progeny marker for steelhead

Creator:: Shippentower, Gene E.
Abstract:: This study was undertaken to determine if strontium chloride could be used to create a trans-generational otolith mark in steelhead (Oncorhynchus mykiss). I completed two strontium injection trials and a survey of juvenile steelhead from various steelhead hatcheries. The two trials measured Sr:Ca ratios in otoliths in response to injections...
Resource Type:: Masters Thesis
Full Text:: assessed the effect of treatment on the survival and growth of progeny from treated females. Finally, I

Passive sampling devices as biological surrogates for evaluating seasonal bioavailability of hydrophobic organic contaminants in surface water

Creator:: Sethajintanin, Doolalai
Abstract:: The seasonal distribution of bioavailable organochiorine contaminants in surface water and the potential environmental factors influencing their bioavailability were evaluated. The study was carried at the lower Willamette River at Portland Harbor, Oregon where surface water runoff varied according to season. Bioavailable water concentrations of DDTs and PCBs were determined...
Resource Type:: Dissertation
Full Text:: bioavailable distributions of organochiorine contaminants was compound- and site-specific. Bioavailable DDTs

ScholarsArchive@OSU

Molecular and cellular mechanisms of aromatic hydrocarbon axonopathy

Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Diethylnitrosamine, ethylnitrosourea, and dimethylbenz(a)anthracene DNA binding studies in the rainbow trout

Growth of lactococci relative to antibiotic and quaternary ammonium compounds

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Total exposure profiles of azinphosmethyl and azinphosmethyl-oxon to orchard workers in the Pacific Northwest

Development of a progeny marker for steelhead

Passive sampling devices as biological surrogates for evaluating seasonal bioavailability of hydrophobic organic contaminants in surface water

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