The antimutagenic potency of wheat grain and berry extracts was studied in vitro against several heterocyclic amines (HCAs) using the Salmonella mutagenicity assay and the anticarcinogencity of wheat grain was studied in vivo using the rat colonic aberrant crypt focus assay. Wheat bran, which binds HCAs in vitro, as well...
Marine algae have been recognized as a rich resource of new
and unusual organic molecules with diverse biological properties.
The current need to develop new antifungal, anticancer, antibiotic
and antiviral drugs has led to an intense research effort into the
discovery, isolation and structure determination of potential
medicinal agents from...
Characterization of the 5' flanking region of rainbow trout ki-ras gene was begun with the cloning and sequencing of this region by the inverse PCR technique and dideoxynucleotide chain termination method. In total, a nucleotide sequence of 1080 bp upstream from the first coding ATG was sequenced. Although this region...
Some parasites may modify the behavior of their
hosts. Altered behaviors may: 1) benefit the host in
that they defend against the pathogen, 2) benefit the
pathogen and represent manipulations of the host
response, and 3) benefit neither the host or the
pathogen and simply be a product of the...
There is plenty of evidence from epidemiology studies
supporting a link between certain components in the human
diet and cancer incidence. It is estimated that 3-4 million
annual cases of cancer could be prevented worldwide just by
changing dietary habits. In parts of the world where
vegetables and fruits constitute...
Indole-3-carbinol (I3C), the most abundant metabolite of glucobrassicins, is
found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and
cauliflower. I3C has been shown to have anticarcinogenic activity against many
chemical carcinogens in multiple target organs in animal models. However, the
anticarcinogenic activity of I3C is considered indirect since...