Models that assess the risk to biodiversity from landscape change can help
communities prioritize planning decisions. Accurate representation of the ecology and
life history traits of species is necessary. This study introduces the use of habitat
quality in a biodiversity risk model to determine the significance of habitat quality when...
Background: Some groups of breast cancer survivors bear a greater burden of diminished quality of life than others. Self-identified lesbians, or women who partner with other women in romantic and spousal relationships, are one group of women that has been hypothesized to experience and report poorer quality of life compared...
BACKGROUND: To examine the association between objectively measured light-intensity and moderate-to-vigorous-intensity physical activity (MVPA), sedentary behaviors, and biological markers in a national
sample of U.S. pregnant women, as few studies have examined these relationships among this population.
METHODS: The sample of noninstitutionalized U.S. civilians was selected by a complex, multistage...
Zebrafish are a powerful model organism to study disease. Like other animal models, Danio rerio colonies are at risk of pathogenic infection. Microsporidia, a group of intracellular fungus-like parasites, are one potential threat. Microsporidian spores germinate and spread causing pathological changes in the central nervous system, skeletal muscle, and other...
Tolerance of adult zebrafish and efficacy of emamectin benzoate and ivermectin in eliminating Pseudocapillaria tomentosa infection were evaluated. In the tolerance study, behavioral changes, fecundity, histopathology, and mortality were evaluated for in-feed administration of emamectin (0.05, 0.10, and 0.25 mg/kg) and ivermectin (0.05 and 0.10 mg/kg). All doses of emamectin...
Freeze-drying, or lyophilization, has shown great promise in addressing many of the logistical challenges of storing and preserving red blood cells (RBCs). A crucial part of any RBC lyophilization protocol is the primary drying temperature, which affects the sample drying rate and the dried cake’s ability to form a stable...
BACKGROUND: Parents play a significant role in shaping youth physical activity (PA). However, interventions targeting PA
parenting have been ineffective. Methodological inconsistencies related to the measurement of parental influences may be a
contributing factor. The purpose of this article is to review the extant peer-reviewed literature related to the measurement...
Significance: Parasite survival and virulence relies on effective defenses against reactive oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) are ubiquitous enzymes now thought to be central to such defenses and, as such, have potential value as drug targets and vaccine antigens. Recent Advances: Plasmodial and...
Ebola virus causes an acute hemorrhagic fever lethal in primates and rodents. The contribution of host immune factors to pathogenesis has yet to be determined and may reveal efficacious targets for potential treatment. In this study, we show that the interleukin (IL)-10 signaling pathway modulates Ebola pathogenesis. IL-10 [superscript -...
BACKGROUND: Patients receiving hospice or palliative care often receive antimicrobial therapy; however the effectiveness
of antimicrobial therapy for symptom management in these patients is unknown.
OBJECTIVE: The study’s objective was to systematically review and summarize existing data on the prevalence and
effectiveness of antimicrobial therapy to improve symptom burden among...