We live in an exciting time for biology. Technological advances have made data collection easier and cheaper than we could ever have imagined just 10 years ago. We can now synthesize and analyze large data sets containing genomes, transcriptomes, proteomes, and multivariate phenotypes. At the same time, society's need for...
Cyprinid herpesvirus 3 (CyHV-3), commonly known as koi herpesvirus (KHV), is a member of the Alloherpesviridae and is a deadly pathogen for koi and common carp, Cyprinus carpio. It causes severe gill necrosis and nephritis, dermal ulceration and hemorrhage, and mass mortality of up to 100% of affected fish. Fish...
Koi herpesvirus (KHV) is a pathogen affecting common carp and ornamental koi with high morbidity and mortality. Currently, no effective treatment or vaccine is available against this virus. Cullin RING ubiquitin ligases (CRLs) are a class of host proteins that facilitate infection of DNA viruses, such as herpesviruses. Inhibitors of...
Koi herpesvirus (KHV) infection is associated with high mortalities in both common carp (Cyprinus carpio carpio) and koi carp (Cyprinus carpio koi) worldwide. Although acute infection has been reported in both domestic and wild common carp, the status of KHV latent infection is largely unknown in wild common carp. To...
I explore the proposition that evolutionary biology is
currently in the midst of its greatest period of synthesis. This period,
which I call the Ongoing Synthesis, began in 1963 and continues at
the present time. I use analysis of citations, conduct, and content to
compare the Ongoing Synthesis to widely...