Liver X receptor (LXR), farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) are adopted orphan nuclear receptors that function as lipid sensors. These receptors respond to cellular lipid levels and regulate the expression of target gene. Previously, it was demonstrated that low doses of chlordecone (CD) pretreatment disturbed exogenous...
Effect of diets varying in amount of cholesterol and
polyunsaturated to saturated fatty acid ratio (P/S) on plasma lipid
levels and lecithin:cholesterol acyltransferase (LCAT) activity was
determined in fourteen young adult male subjects during a 13-week
experimental period in a crossover design.
Control diet was fed for two weeks prior...