Background
Bcl11b, previously CTIP2, is a zinc finger nuclear transcription factor involved in the development of keratinocytes, teeth, T lymphocytes, and nervous tissue. Expression of Bcl11b has been reported in human head and neck squamous cell carcinoma (HNSCC) and increased expression correlates with poorly differentiated tumors. This study aimed to...
Zebrafish (Danio rerio) have become an increasingly important model organism for cancer research. There are several cancer models in which neoplasms are induced chemically or genetically. However, spontaneous (unknown etiology) neoplasms are rather common in zebrafish, particularly in older fish. For over a decade, spontaneous intestinal neoplasia and preneoplastic intestinal...
Fanconi's Anemia (FA) is an autosomal recessive chromosomal instability disorder. The
symptoms include congenital abnormalities, defective hematopoiesis (formation of cells
of the blood), and high risk of developing acute myeloid leukemia and solid tumors.
Fanconi researchers have long been puzzled by how Fanconi Anemia (FA) cells, which
are known to...
Copper deficiency and Mo-induced Cu deficiency are nutrition
problems of ruminant livestock in the Burns and Klamath Falls area
of Oregon. Chemical analysis of plant and soil samples was used to
survey Cu and Mo levels in forage in these areas. The objectives
were to assess the possibility of animal...
A series of four trials was conducted to evaluate activated
sewage sludge (AcSS) as a protein source. In the first trial the protein
efficiency ratio (PER) of sun-dried and auto-claved, sun-dried
AcSS was measured with rats. Growth of AcSS-fed rats was extremely
poor as compared to those rats fed casein,...
The gray-tailed vole (Microtus canicaudus) demonstrated a
requirement for selenium and vitamin E. Animals deficient in both
nutrients suffered from liver necrosis and an unthrifty condition
characterized by inappetence, profuse diarrhea, and swollen eyes.
Vitamin E appeared less effective than selenium as a prophylaxis
against this syndrome.
Total body weights,...