Oxidative stress is recognized as an important underlying factor in the
pathogenesis of many degenerative diseases as well as normal senescence. The
free radicals, reactive oxygen species (ROS) and electrophiles produced during
oxidative stress are capable of modifying nucleic acids, lipids and proteins. There
are a variety of oxidative modifications...
The coastal zone is the area where the land, sea, air meet.
It has a unique combination of characteristics which favor human
development, trade and industry.
"Coastal climates are more moderate and stable than those of
the interior of the continents, and are usually associated with
sufficient rainfall to sustain...
This chapter describes a mass spectrometry-based strategy that facilitates the unambiguous identification and characterization of proteins modified by lipid peroxidation-derived 2-alkenals. The approach employs a biotinylated hydroxyl amine derivative as an aldehyde/keto reactive probe in conjunction with selective enrichment and tandem mass spectrometric analysis. Methodological details are given for model...
The northwest coast of Mexico is accountable for almost 70 % of the
country´s fishery production. This region, which includes the Gulf of
California and the Pacific coast of the Baja California Peninsula, is also
extremely important in terms of biodiversity and the presence of endemic
species. Consequently, eleven marine...