Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
Mycobacterium avium is an intracellular pathogen that is associated with disseminated
infection, especially in patients with acquired immunodeficiency syndrome (AIDS). It
appears that patients with AIDS acquire M. avium mostly through the intestinal tract,
and that bacteria enter the intestinal wall at the terminal ileum. Previous studies have
found that...