Polyethylene terephthalate (PET) polymer has been the material of choice for packaging industry as a result of its excellent mechanical and physical properties. These properties are highly dependent on the microstructure, chemistry, and processing conditions of this material. PET is often oriented in the machine direction (MD), the transverse direction...
Poor aqueous solubility of a large number of newly discovered chemical entities is posing a significant challenge for the formulation industry and is delaying their drug development. The number of formulation techniques available to solubilize these poorly soluble molecules is very limited. In addition to that, traditional formulation methods involve...
Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram-positive bacteria, was incorporated into novel block copolymer constructs and tested for retained antibacterial activity. Covalent coupling was achieved by chemical modification of the N-terminal isoleucine to introduce a thiol group. Thiolated nisin derivatives were then linked to poly[ethylene...