Non-coding ribonucleic acid (ncRNA) is of interest for its diverse roles in cell and viral biology. RNA molecules vary greatly in terms of size, structure, and function. In recent years, the modification of existing RNA structures has been used for biochemical methods of enormous impact including CRISPR and RNAi methods....
Hydrogels have been attractive for use as a medium in porous flow studies,
but have always been limited in this role because of their poor mechanical properties.
This project analyzes and tests two recently developed hydrogels,
poly(methacrylamide-co-methacrylic acid) (PMM), and a heat-treated long chain
PVA hydrogel. Particle image velocimetry (PIV)...
Paper microfluidic devices are capable of processing fluids using capillary flow in materials that are lower cost than the standard materials used in microfluidics. Due to the low cost of their fabrication and minimal requirements for instrumentation, paper microfluidic devices are ideal for use in low-resource settings. They have the...
Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled
signaling pathways. Prior research suggested that some isoforms of PLC-β may exist
and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation
assays of differentially-tagged PLC-β constructs and sizeexclusion
chromatography of native PLC-β support homodimerization...
We used metatranscriptomics to study the gene transcription patterns of microbial plankton (0.2 to 64 μm) at a mesohaline station
in the Chesapeake Bay under transitions from oxic to anoxic waters in spring and from anoxic to oxic waters in autumn.
Samples were collected from surface (i.e., above pycnocline) waters...
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Mary Doherty,b Dong Yoon Lee,b Michael Owens,b James P. Shapleigh,a JeffreyC. Cornwell,b
Byron C