The free-radical theory of aging proposes that intracellular accumulation of oxidative damage caused by
reactive oxygen species (ROS) is responsible for the process of senescence. ROS are produced during
normal aerobic metabolism and have been shown to cause numerous cellular and sub-cellular defects
that lead to termination of the cell...
The gonadal steroids, testosterone and estradiol, are known to be important
modulators of neuronal functions and behaviors in most vertebrate species. These
steroid hormones also elicit changes in neuropeptide synthesis and secretion, alter
specific neurohormone receptor levels, and alter neuronal morphology and
electrophysiology. Many of the actions of androgens and...
Many studies suggest that weedy plant species are most successful when
soil nitrogen in abundant. Consequently, I used soil nitrogen manipulations to
determine if altering nitrogen would affect the establishment of both weedy and
native plant species in a western Oregon wetland prairie. In two studies, we
added carbon amendments...
I studied the water relations traits, twig conductivity, C'3 isotopic composition,
and wood density of three conifer and five angiosperm species in western Oregon. This
study took place from spring 2002 to fall 2003 on four sites. Species were selected to
represent the diversity of drought tolerance of woody plants...
The near physical environment is believed to be an integral component in creating quality learning and classroom environments for young children. Free-choice play periods during preschool daily curriculums are a widespread component of preschool early childhood education. Research has demonstrated that the presence of houseplants may be a contributor to...
Shortnose Sucker (Chasimistes brevirostris) and Lost River Sucker (Deltistes luxatus) are endemic to the Upper Klamath Basin of Southern Oregon and Northern California. Populations of these fishes have been dwindling since the 1960’s and both species where listed to as endangered in 1988. Poor recruitment is thought to be a...
Chitosan based hemorrhage control dressings provide effective external hemorrhage control while having few side effects. Known residual contaminants present in chitosan formulations include endotoxins and proteins known to stimulate gene expression in the liver. This study investigated gene expression in the liver using rat bio-compatibility models to gain knowledge regarding...
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Subcutaneous Chitosan Patch Formulations
Andrew Colburn1, Leslie Dyal, Ph.D.2 and John Mata Ph.D.2
Oregon
Chitosan based hemorrhage control dressings provide effective external hemorrhage control while having few side effects. Known residual contaminants present in chitosan formulations include endotoxins and proteins known to stimulate gene expression in the liver. This study investigated gene expression in the liver using rat bio-compatibility models to gain knowledge regarding...
Full Text:
Based Hemostatic Control Patch in Rat Models
By
AndrewJ. Colburn
A thesis submitted to
Oregon
The collapse of the I-35W Bridge in Minneapolis, MN in 2007 prompted an investigation into the design and inspection of the steel truss bridges. Further investigation into the collapse revealed that a gusset plate experienced sway buckling, causing the bridge failure. This bridge failure motivated research into the analysis and...