In order to better understand the relationships among current Nostocales cyanobacterial blooms, eight genomes were sequenced from cultured isolates or from environmental metagenomes of recent planktonic Nostocales blooms. Phylogenomic analysis of publicly available sequences placed the new genomes among a group of 15 genomes from four continents in a distinct...
In early August 2014, the municipality of Toledo, OH (USA) issued a ‘do not drink’ advisory on their water supply directly affecting over 400,000 residential customers and hundreds of businesses (Wilson, 2014). This order was attributable to levels of microcystin, a potent liver toxin, which rose to 2.5 μg L⁻¹...
Gall-associated phytopathogens have unique evolutionary histories that haveshaped both their modes of infection and genomic structures. Pathogenicity of the gall-associated plant pathogens of the Rhodococcus, Agrobacterium, and Rathayibactergenera is mediated by horizontally acquired virulence loci. The relative ease of gainand loss of the virulence loci has confounded accurate characterization of...
Using bulked segregant analysis, five RAPD markers were identified that were
linked in coupling to a gene conferring complete resistance to eastern filbert blight caused
by Anisogramma anomala (Peck) E. Muller in hazelnut (Corylus avellana L.). Two
modified backcross populations were inoculated and scored for resistance to the pathogen
and...
Sediment-associated gross primary production, oxygen uptake, microalgal biomass expressed as chlorophyll a concentration, macroalgal biomass and total organic matter concentration expressed as ash-free dry weight were measured monthly at medium sand, fine sand and coarse silt sites between 0.5 m and 2.0 m above MLLW during an entire year at...
Amyotrophic lateral sclerosis (ALS) is a devastating disease characterized by the progressive degeneration of motor neurons. Dominantly-inherited mutations to the antioxidant enzyme Cu,Zn superoxide dismutase (SOD1) cause 3-6% of all ALS cases. The complete mechanism behind the toxicity of mutant SOD1 remains unclear, although significant evidence points to aberrant or...