Index Catalog // ScholarsArchive@OSU

Creator:: Zwida, Khawla
Abstract:: Throughout most of the developed world, surgical sterilization via gonadectomy has become a common tool for combating the overpopulation of unwanted dogs as well as to eliminate the risk of reproductive diseases in pet dogs. In the dog as in other normal adult mammal, the hypothalamus secretes gonadotropin-releasing hormone (GnRH),...
Resource Type:: Masters Thesis
Full Text:: pet dogs. In the dog as in other normal adult mammal, the hypothalamus secretes gonadotropin

Creator:: Viall, Austin K.
Abstract:: The serotonergic system plays a significant regulatory role in osteoblast differentiation and proliferation. Serotonin (five-hydroxytryptamine or 5HT) may promote or inhibit osteoblast proliferation depending upon the serotonin receptor isoforms expressed by the cell. Classically, 5HT receptor 1B (5HTR1B) reduces osteoblast proliferation by inhibiting phosphorylation of the cAMP response element binding...
Resource Type:: Masters Thesis
Full Text:: skeletal malignancy of the dog.1 Canine osteosarcoma has long been considered a natural analog of human

Creator:: Paquette, Colleen Elizabeth
Abstract:: Zebrafish (Danio rerio) have become an increasingly important model organism for cancer research. There are several cancer models in which neoplasms are induced chemically or genetically. However, spontaneous (unknown etiology) neoplasms are rather common in zebrafish, particularly in older fish. For over a decade, spontaneous intestinal neoplasia and preneoplastic intestinal...
Resource Type:: Masters Thesis
Full Text:: laboratory species. Gastric cancer has been reported most commonly in the dog. Other species noted for

Creator:: Xu, Tanjin
Abstract:: An important impact of the genome technology revolution will be the elucidation of mechanisms of cancer pathogenesis, leading to improvements in the diagnosis of cancer and the selection of cancer treatment. Integrated with current well-studied massive knowledge and findings about the role of protein-coding mutations in cancer, demystifying the functional...
Resource Type:: Masters Thesis
Full Text:: for Cancer Noncoding Mutation Recurrence Abstract approved: Stephen A. Ramsey An important impact

Creator:: Coleman, Daniel J.
Abstract:: Melanoma is the deadliest form of skin cancer, arising from malignant transformation of pigment-producing melanocytes. The primary risk factor for melanoma and other skin cancers is DNA damage resulting from unprotected solar ultraviolet radiation (UVR). If incorrectly repaired, this damage can result in incorporation of mutations that cause aberrant cell...
Resource Type:: Dissertation
Full Text:: is the deadliest form of skin cancer, arising from malignant transformation of pigment-producing

Creator:: Hughes, Kelly L.
Abstract:: The endogenous circadian clock is an intracellular transcriptional feedback loop timing daily patterns of multiple biological rhythms within a 24-hour period. Disturbance in various rhythms leads to alteration of normal biological processes including cellular proliferation and tumor suppression. Endogenous circadian clock rhythms have been found to be disrupted in breast...
Resource Type:: Masters Thesis
Full Text:: Expression in Canine Mammary Cancer Abstract approved

Creator:: Chagani, Sharmeen
Abstract:: Cutaneous melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment-producing melanocytes, with a diagnosis of metastasis indicating a median survival rate of less than a year. Solar ultraviolet (UV) radiation, especially childhood sun exposure, is an important etiological risk factor of melanoma. This DNA damage...
Resource Type:: Dissertation
Full Text:: melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment

ScholarsArchive@OSU