One fundamental concern in conservation biology is species abundance. For many taxa, however, these data are costly to obtain via direct observation and thus limited in geographic or temporal scope. Very high-resolution satellite imagery provides a means to address these limitations and provide remotely-sensed counts of large, colonial species. We...
This white paper gives an overview of the software applications used by university presses to publish digital monographs. In addition, we will look at routes taken by university presses to move from all print to some e-publishing and list the supplemental online content that is typically offered for a fee.
The eighteenth-century female of sensibility was characterized by delicate nerves that allowed her to feel her surroundings and enabled her to choose virtue over vice more consistently than males. While females were considered virtuous, their "innate" delicacy or weakness became their dominant trait and the true focus of male admiration....
Managing riparian areas in the dry forests of the intermountain west for diverse public values can create conflict, potentially limiting social acceptance in landscape-scale restoration projects. This thesis examined accelerated landscape-scale restoration as part of a broader shift toward ecosystem management on national forestland, which incorporates social values into forest...
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Emily Jane Davis
Managing riparian areas in the dry forests of the intermountain west for
Chemical compounds produced by organisms, or natural products, are excellent sources of inspiration for anticancer pharmaceutical discovery (Rodrigues et al., 2016). Microtubule targeting agents are a specific class of compounds, often discovered from natural sources, that have been developed as clinically successful anticancer therapies (Steinmetz and Prota, 2018). In the...
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JaneE. Ishmael, Ph.D.
Chemical compounds produced by organisms, or natural products, are
Autophagy, a homeostatic degradation pathway, has a role in promoting cell survival under stress conditions, but can also promote cell death under conditions of sustained stress. This project investigates the cytotoxic potential of coibamide A and other natural products in autophagy-deficient and wild-type mouse embryonic fibroblasts (MEFs). Wild-type MEFs were...
Background information is presented that provides historical perspectives on the field of mycology in the Pacific Northwest and its role in forest management. The series of events and decisions that have led to previous studies (or lack of studies) in the field also dictate the directions of current research. Culture,...
EF-hand proteins are a conserved family of proteins that are modulated by divalent cations and regulate diverse cellular activities. In the present study we characterized the molecular determinants of myosin regulatory light chain (RLC) interaction with several subunits of the N-methyl-D-aspartate (NMDA)-type glutamate receptor. Myosin RLC is an EF-hand protein...
Natural products from both terrestrial and marine sources represent a significant source of novel drug leads, and have previously been developed into clinically-approved agents for the treatment of various human diseases. This work represents the biological characterization of the mechanistic basis for activity of several natural product structures in models...