Peroxisome proliferator-activated receptors (PPARs) are members of a
large group of ligand-regulated transcription factors that includes nuclear
receptors for steroid and thyroid hormones, retinoids and vitamin D₃.
Synthetic fibrates and thiazolidinediones that bind to and activate PPARs are
used efficaciously in humans to remedy hypertriglyceridemia and non-insulin
dependent diabetes mellitus,...
This paper examines ways in which natural resource management – NRM – may be decolonized in order to better serve Hawaiʻi communities. Expressed needs for diversity in NRM has brought about inclusion of traditional ecological knowledge in recent years. Here, traditional ecological knowledge is redefined as ʻIK, ʻike kupuna –...
In our previous column, we reviewed Wikipedia's role as a global encyclopedia and demonstrated how it can be paired with the ACRL Framework (Dowell & Bridges, 2019). This column will expand on its use, highlighting several approaches for employing Wikipedia as an educational tool through programs, assignments, and methods by...
The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
A cultural landscape analysis of two historic cemeteries in St. Paul, Oregon demonstrates that the residents of this early community were unknowingly using grave markers to express their worldview and the identities that they felt were most important. Because of the historical and cultural development of this community as the...
Ceria nanoparticles are of interest owing to their interesting properties like photo-absorption and ability to absorb oxygen. Several batch synthesis routes exist however these methods often lack particle size control, result in agglomeration and typically require high temperature processing. In this paper, a continuous flow microchannel synthesis method based on...
In the early part of his philosophical career, Paul Ricoeur worked out a general theory of symbols which he illustrated with the symbols of evil. He subsequently explained this theory in several essays (his final major statement on symbols can be found in Interpretation Theory: Discourse and the Surplus of...