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  • Characterization of antibiotic resistant enteric bacteria that contaminate vegetables

    Creator:
    Salama, Maysoon
    Abstract:
    Previous studies revealed the high incidence of drug resistant bacteria from foods. In this study, market vegetables were tested for their contamination with antibiotic resistant (ABR) enteric bacteria. A total of 402 bacterial strains from surface vegetables (e.g., lettuce) and 321 from root vegetables (e.g., carrots) were examined for their...
    Resource Type:
    Masters Thesis
    Full Text:
    ) drug therapy. The development of clinically relevant antimicrobial resistance in bacteria is a

  • Antibiotic Resistance Gene Transfer in Oysters as a Result of Fecal Pollution

    Creator:
    Cooper, Rebecca
    Abstract:
    Antibiotic resistance is an increasing problem in many species of bacteria today, with pathogens an important focus. Fecal contamination of shellfish is already a concern due to potential pathogens. This report examines the possibility of resistance gene transfer between microbes, due to fecal bacteria, within the oyster. In this study,...
    Resource Type:
    Undergraduate Thesis
    Full Text:
    Antibiotic resistance has been shown to occur in a

  • Drug resistance indexing Enterobacter as a method of identifying food contamination of public health significance

    Creator:
    Shadbeh, Maryam
    Abstract:
    The Enterobacter are often found in the feces of man and other warm blooded animals but have limited use as indicators of fecal contamination of foods and water since they are also often found as natural flora of non-fecal environments such as water and plants. This study proposes a method...
    Resource Type:
    Masters Thesis
    Full Text:
    Master of Science in Food Science and Technology presented on May 28, 1980. Title: Drug Resistance

  • Prevalence and Fate of Antibiotic-resistant E. coli in Municipal Wastewater Treatment Plants across Oregon

    Creator:
    Khorshidi Zadeh, Marjan
    Abstract:
    Wastewater treatment plants are considered one of the main sources and reservoirs of antimicrobial resistance (AMR). This study investigated the prevalence of 8 different phenotypes of AMR, multi-drug resistant (MDR), and extended-spectrum beta-lactamases (ESBL) producing E. coli in 17 wastewater treatment plants across Oregon in winter and summer of 2019...
    Resource Type:
    Masters Thesis
    Full Text:
    ..................................................... 9 2.5 Regulations Governing Antibiotics and Antibiotic Resistance in the US

  • Growth and development of tetracycline resistant Chlamydia suis

    Creator:
    Lenart, Jennifer
    Abstract:
    Tetracycline is a front line antibiotic for the treatment of chlamydial infections in both humans and animals, and the emergence of tetracycline resistant (tet[superscript R]) Chlamydia is of significant clinical importance. Recently, several tet[superscript R] chlamydial strains have been isolated from swine (Sus scrofa) raised in production facilities in Nebraska....
    Resource Type:
    Masters Thesis
    Full Text:
    Regulation of Tetracycline Resistance Genes 23 Transfer of Tetracycline Resistance 25 Antibiotic Use in

  • Recombination, resistance, and drug discovery in Chlamydia

    Creator:
    Sandoz, Kelsi
    Abstract:
    The intracellular life cycle of Chlamydia has been difficult to study due to the inability to genetically manipulate the bacteria. As a result, indirect methods have been employed to study the pathogen and the aspects that contribute to its unique intracellular life cycle. A wide variety of laboratory adapted strains,...
    Resource Type:
    Dissertation
    Full Text:
    Recombination, Resistance, and Drug Discovery in Chlamydia 2 Antibiotic Resistance in Chlamydiae

  • Characterization of the genomic islands from tetracycline-resistant Chlamydia suis

    Creator:
    Dugan, Jae
    Abstract:
    Tetracycline (Tet)-resistant strains of Chlamydia suis were isolated from swine farms in the Midwest. The isolation of the resistant strains was significant because Tet is an antibiotic used to treat infections by veterinarians and doctors. One of the tetracycline (Tet)-resistant strains, R19, was able to survive in Tet up to...
    Resource Type:
    Dissertation
    Full Text:
    There have been several reported cases of apparent drug resistance in both human and reference

  • Variation in Antibiotic Susceptibility of Uropathogens by Age among Ambulatory Pediatric Patients

    Creator:
    McGregor, Jessina C., Quach, Yennie, Bearden, David T., Smith, David H., Sharp, Susan E., and Guzman-Cottrill, Judith A.
    Abstract:
    We compared uropathogen antibiotic susceptibility across age groups of ambulatory pediatric patients. For Escherichia coli (n=5,099) and other Gram-negative rods (n=626), significant differences (p<0.05) existed across age groups for ampicillin, cefazolin, and trimethoprim/sulfamethoxazole susceptibility. In E. coli, differences in trimethoprim/sulfamethoxazole susceptibility varied from 79% in children under 2 to 88%...
    Resource Type:
    Article
    Full Text:
    less than six years of age (Hersh, et al., 2011). Antibiotic resistance is a complicating factor in

  • Antibiotic Resistance in Septic Sludge and Receiving Environments of Ho Chi Minh City, Vietnam

    Creator:
    Schutzius, Genevieve Conyers
    Abstract:
    Approximately ninety percent of urban Vietnamese households are connected to septic tanks, from which up to three-quarters of the sludge is reported to be dumped into waterways in residential areas. Vietnam has a considerable prevalence of antibiotic misuse and resultant antibiotic-resistant bacteria (ARB) in the human microbiome. Due to the...
    Resource Type:
    Masters Thesis
    Full Text:
    Environmental Engineering presented on August 20, 2018. Title: Antibiotic Resistance in Septic Sludge and

  • Evaluation of peptide phosphorodiamidate morpholino oligomers as a novel antibiotic therapy

    Creator:
    Kaller, Margo
    Abstract:
    Peptide-phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA mimics that bind and silence gene targets. Through designing PPMOs that silence essential or resistance genes in pathogens, these antisense oligomers could be utilized as novel antimicrobials. Towards this end, my thesis employed minimum inhibitory concentration assays (MICs) to identify PPMOs capable of...
    Resource Type:
    Masters Thesis
    Full Text:
    .. ..................................................................................................................... 48 5.2 Resistance Gene Screening for PPMO Drug Targets in Combination with Standard Antibiotics