Billions of pounds of bisphenol A (BPA) are produced annually around the globe for the manufacture of numerous consumer products, including polycarbonate food and water containers, the protective resin linings of food cans, thermal printing paper, and dental fillings. BPA exposure during nervous system development has been associated with learning...
Two experiments were conducted to determine whether in
ewes uterine concentrations of estrogen and progesterone
receptors are affected by the presence of a conceptus or by
the hormonal milieu associated with extremes in photoperiod
to which ewes are exposed.
In Exp.1, nine mature ewes were unilaterally
ovariectomized by removing an...
The gonadal steroids, testosterone and estradiol, are known to be important
modulators of neuronal functions and behaviors in most vertebrate species. These
steroid hormones also elicit changes in neuropeptide synthesis and secretion, alter
specific neurohormone receptor levels, and alter neuronal morphology and
electrophysiology. Many of the actions of androgens and...
The endogenous circadian clock is an intracellular transcriptional feedback loop timing daily patterns of multiple biological rhythms within a 24-hour period. Disturbance in various rhythms leads to alteration of normal biological processes including cellular proliferation and tumor suppression. Endogenous circadian clock rhythms have been found to be disrupted in breast...