Eye plaque brachytherapy is an established technique for the treatment of ocular melanoma that allows for the preservation of the affected eye as well as visual function. A common treatment planning system for eye plaque procedures, Plaque Simulator (PS), assists physicists in calculating the radiation dose to the tumor and...
The purpose of this study is to examine the challenges of accepting and commissioning a new treatment planning system for eye plaque brachytherapy. Currently Oregon Health and Science University (OHSU) utilizes v5.3.9 of the Plaque Simulator software to plan all of its eye plaque brachytherapy cases. However, v5.3.9 is no...
Introduction: In today's radiological quest to pacify and eliminate cancer, it has become conventional in cancer treatment facilities to implement advanced guidance or target localization systems with the goal of maximizing accuracy of radiation dose delivery to a tumor while simultaneously minimizing normal tissue complication. At the Oregon Health &...
As the field of radiation therapy evolves new treatment techniques will be
established. An example of an evolving treatment technique is respiratory gated
radiation therapy (RGRT). Research and studies have shown that RGRT can be used
to account for tumor motion as a result of respiratory motion. With evolving
technology...
The cell survival curve is the only means by which to both qualitatively and
quantitatively assess morphologic alterations directly resulting from in vitro irradiation of
the cell. A ⁶⁰Co cell survival curve experiment has successfully demonstrated the
response of the AtT-20 clone mammalian cell line to the effects of gamma...
Cancer is one of the leading causes of death in the U.S., and new approaches to control cancer are constantly sought. This dissertation is comprised of two parts: (i) improving the uptake and retention of gadolinium in tumors for potential gadoliniumneutron capture therapy (Gd-NCT) and (ii) integration of gemcitabine or...