The development of simple, rapid, and sensitive methods for thiophenol detection is of great importance in various fields, including environmental monitoring and food quality. Here, we present a novel approach for the colorimetric detection of thiophenols using gold nanoparticles (AuNPs) as the sensing platform. AuNPs aggregate in the presence of...
The majority of people suffer from back pain at some point in their lives. Back pain is the leading cause of disability globally, ahead of 290 other conditions1. Over one million people in the United States receive spine surgery annually2. This thesis looked at five standard surgical procedures performed on...
Multicellular coordination in response to environmental stimuli is essential in biology, and this coordination is often achieved by a division of labor to establish leaders and followers in a cell population. This is called emergent leadership, but how a cell adopts its role and effectively exchanges information with peers is...
Microfluidic devices have enabled lab-on-a-chip (LOC) systems that allow for complex sample analysis and preparation in a compact form factor. One technology that may benefit from a microfluidic approach and further miniaturization is flow cytometry. Flow cytometry is an analysis technique for enumerating and characterizing populations of cells; this is...
Electroanalytical techniques allow scientists and engineers to characterize bulk solutions as well as interfaces. Potentiostats are commonly used by researchers in a variety of disciplines to analyze the chemistry which occurs at a working electrode surface. Advancements in microelectronics and the proliferation of open-source designs have allowed researchers to construct...
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ElainFu, Committee Member, representing the School of Chemical, Biological, and
Environmental
Inkjet-printed p-type copper(I) iodide-based TFTs were successfully fabricated. As-printed copper(I) halide semiconductor films, such as CuI, CuBrI, and CuClI, were used as p-type active channel layers for TFTs. The entire process of the TFTs fabrication was maintained under 150 °C, which is compatible with flexible plastic substrates and transparent glass...
The concept of reducing laboratory operations into microfluidic devices has been an attractive area of research for several decades. Due to several advantages of porous-media microfluidic devices including low mass, portability, power-free fluid transport, and the ability to store dried reagents in the porous structures, these devices show great promise...
To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
The general theme of this dissertation is the development of new analytical sensors to quantitatively study biological and environmental samples in aqueous and non-aqueous environments. A platinum ultramicroelectrode (UME) and a unique carbon-based pH microprobe were used to design a new SECM-based electrochemical bioassay. The Pt UME was used to...
Within the past decade, the continued-scaling of CMOS processes and improvements in industry mixed-signal integrated-circuit designs have enabled a rapid decrease in the cost, form-factor, and power for point-of-care diagnostics and electrochemical instrumentation. Similarly, advances in low-power RF designs have prompted entire System-on-Modules supporting widely varied Internet-of-Things (IoT) applications. The...