Background: Alcohol is a nonessential nutrient widely consumed throughout the world. Chronic alcohol abuse is associated with numerous adverse skeletal effects. However, prior to this study, the effects of alcohol abuse on intracortical bone remodeling in an animal model had not been investigated. Reduced intracortical bone remodeling could impair repair...
Chronic heavy alcohol consumption is a risk factor for cortical bone fractures in males. The increase in fracture
risk may be due, in part, to reduced bone quality. Intracortical (osteonal) bone remodeling is the principle
mechanism for maintaining cortical bone quality. However, it is not clear how alcohol abuse impacts...