Index Catalog // ScholarsArchive@OSU

Development and Characterization of Novel Muffin Products for Promoting Sustainability

Creator:: Shih, Yi-Ting
Abstract:: Brewers' spent grain (BSG), the byproduct from beermaking, is a good source of protein and dietary fiber and may be utilized as a functional ingredient for food applications such as bakery goods. Starch-based film is well-known for its safety, edibility, and renewability. Starch films with the incorporation of cellulose nanofiber...
Resource Type:: Masters Thesis
Full Text:: career and life. I would also like to recognize Dr. Dave Stone, Dr. Andrew Ross, and Dr. Adrian F

Impact of Vitamin E Deficiency on Hepatic Gene Expression of CRAL_TRIO Family Proteins in a Premier Vertebrate Animal Model

Creator:: Watt, Alexander T.
Abstract:: Vitamin E (vitE) is a group of lipid-soluble antioxidants- of which alpha-tocopherol is the most biologically active and only form considered to be an essential nutrient. Through preferential binding and trafficking, the alpha-tocopherol transfer protein (α-TTP) regulates the concentration of vitE in the body. The impact of vitE deficiency on...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adrian Gombart, Committee Member, representing Department of Biochemistry and Biophysics

Mechanisms that influence the posttranslational modification of the GluN2B subunit in the aged brain

Creator:: Zamzow, Daniel R.
Abstract:: Memory is essential to everyday life. As we age, deficits in memory become apparent. The toll of age-related cognitive impairment can be devastating to families and costly to society. The NMDA receptor is a molecule in the brain that is instrumental in the formation of memories. The receptor is particularly...
Resource Type:: Dissertation
Full Text:: good friend and colleague. I would like to thank my committee members: Fritz Gombart, Pat Chappell

Age-related loss of Nrf2, a novel mechanism for the potential attenuation of xenobiotic detoxification capacity

Creator:: Smith, Eric Jonathan
Abstract:: Nuclear Factor, Erythroid Derived 2, Like 2 (NFE2L2 or Nrf2) is the primary transcription factor in cellular defense against oxidative and xenobiotic stresses in higher eukaryotes. This basic leucine zipper transcription factor regulates over 200 antioxidant, detoxification, and lipid metabolizing genes by binding to the Antioxidant Response Element (ARE; a...
Resource Type:: Dissertation
Full Text:: AUTHORS I would like to acknowledge Dr. Gary F. Merrill for guidance in the execution and

Regulation of BCL11B by post-translational modifications

Creator:: Liu, Xiao
Abstract:: Bcl11b (B-cell lymphoma/leukemia 11b), also known as Ctip2 (Chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2), is a C2H2 zinc finger transcriptional regulatory protein, which is an essential protein for post-natal life in the mouse and plays crucial roles in the development, and presumably function, of several organ systems,...
Resource Type:: Masters Thesis
Full Text:: . Filtz, Dr. Taifo Mahmud, and Dr. Adrian F. Gombart for serving on my committee and for their advice

Ecophylogenetic Characterization of the Gut Microbiome of At-risk Companion and Food Animals

Creator:: Kirchoff, Nicole S.
Abstract:: Agricultural and companion animals are integral to our way of life as they provide us with nourishment, financial resources, transportation, and companionship. However, pets, managed animals in the agricultural industry, as well as wild populations of food animals are all subject to health and mortality risks. The gut microbiome is...
Resource Type:: Dissertation

Underlying Mechanisms of the Anti-inflammatory and Antioxidant Effects of Quercetin in Human Aortic Endothelial Cells : Implications for Vascular Inflammation and Atherosclerosis

Creator:: Li, Chuan
Abstract:: Atherosclerosis is the underlying cause of ischemic heart disease and stroke and is the leading cause of death worldwide, especially in developed countries. As an inflammatory disease of arteries in a hyperlipidemic milieu, expression of adhesion molecules, such as endothelial-leukocyte adhesion molecule-1 (E-selectin) and intercellular adhesion molecule-1 (ICAM-1), on endothelial...
Resource Type:: Dissertation
Full Text:: sincere thanks also go to the rest of my thesis committee: Dr. Jaga Giebultowicz, Dr. Adrian Gombart

Fiction's fatal flaw : misrepresentation of the average scientist

Creator:: Basler, Emily
Abstract:: Fiction facilitates the attribution of unrealistic character traits to scientists, and skews general understanding of the scientific process-- a fatal flaw resulting in self-doubt within undergraduate scientists, and apprehension and distrust in several communities. Misconceptions and the absence of significant ideas were identified by analyzing novels within the “Lab Lit”...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adrian Gombart, Committee Member, representing Biochemistry and Biophysics

The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

Creator:: Hardardt, Elizabeth Ann
Abstract:: This work sought to characterize a link between Vitamin C and nitroglycerin at the level of enzymatic bioactivation. Before we could proceed, we needed to develop a method that sensitively and selectively identified the product of bioactivation, nitrite. We successfully adapted traditional diaminonaphthalene derivatization with the use of stable isotope...
Resource Type:: Masters Thesis
Full Text:: ” Rochefort, Phil Proteau and Adrian “Fritz” Gombart, and all the researchers who developed the use of

Characterization of novel exopolysaccharide producing lactic acid bacteria

Creator:: Garcia, Roberto A., III
Abstract:: Lactic Acid Bacteria (LAB), an important group of organisms in modern food production, are known to secrete a unique compound called exopolysaccharide (EPS). EPS is economically important because it enhances functional properties in food and may confer beneficial health effects to consumers. Novel strains of Lactococcus lactis, Streptococcus thermophilus, and...
Resource Type:: Masters Thesis
Full Text:: thanks to my committee members, Dr. Theo Dreher, Dr. Bruce Geller, and Dr. Adrian Gombart, for their

ScholarsArchive@OSU

Development and Characterization of Novel Muffin Products for Promoting Sustainability

Impact of Vitamin E Deficiency on Hepatic Gene Expression of CRAL_TRIO Family Proteins in a Premier Vertebrate Animal Model

Mechanisms that influence the posttranslational modification of the GluN2B subunit in the aged brain

Age-related loss of Nrf2, a novel mechanism for the potential attenuation of xenobiotic detoxification capacity

Regulation of BCL11B by post-translational modifications

Ecophylogenetic Characterization of the Gut Microbiome of At-risk Companion and Food Animals

Underlying Mechanisms of the Anti-inflammatory and Antioxidant Effects of Quercetin in Human Aortic Endothelial Cells : Implications for Vascular Inflammation and Atherosclerosis

Fiction's fatal flaw : misrepresentation of the average scientist

The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

Characterization of novel exopolysaccharide producing lactic acid bacteria

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