The organic Rankine cycle (ORC) is a versatile approach in the utilization of waste heat in the production of electricity, clean drinking water, and cooling. The efficiency of these cycles must be maximized to make them economical. Parameters for the optimization of ORCs such as evaporator and condenser temperature have...
Heat activated cooling has the potential of utilizing thermal sources that currently go unused such as engine exhaust heat or industrial waste heat. Using these heat sources can provide enhanced energy utilization and reduced fuel usage in applications where cooling is needed. The concept developed here uses waste heat from...
Earth’s mantle extends to nearly 3000 km depth, comprises >80 % of Earth’s total volume, and has the largest influence on the primordial and radiogenic heat budget. Despite its importance, the structure and composition of the mantle is still debated. There are three primary models for Earth’s mantle structure that...
Many D2d-symmetric 2,2',6,6'-tetrasubstituted biphenyls are
readily prepared via net oxidative dimerization of appropriate
1,3-disubstituted benzenes. Conversion of such proprochiral
compounds to useful C2-symmetric chiral biphenyls requires
formal replacement of two substituents on opposing aryl ring
units with alternate groups. This under exploited
desymmetrization tactic has been demonstrated for the
generation...
Seed germination sensu stricto is defined as the physiological events before the radicle tip ruptures the covering tissues. The ability of the radicle to elongate (or germination potential) is observed in developing embryos prior to completion of seed maturation. When embryos at early developmental stages, such as globular, heart, torpedo...
Marine algae have been recognized as a rich resource of new
and unusual organic molecules with diverse biological properties.
The current need to develop new antifungal, anticancer, antibiotic
and antiviral drugs has led to an intense research effort into the
discovery, isolation and structure determination of potential
medicinal agents from...
7,7'-Dihydroxy-8,8'-biquinolyl (azaBINOL) was prepared from 7-hydroxyquinoline via N,N-dimethyl O-quinol-7-yl carbamate by directed ortho-metallation followed by FeCl₃-mediated oxidative coupling of the 8-lithioquinoline intermediate. Saponification of the resulting dicarbamate provided crystalline (±)-azaBINOL in 56% overall yield. 6,6'-Bis(dimethylaminocarbonyl)-7,7'-dihydroxy-8,8´-biquinolyl was prepared from the same dicarbamate by a double anionic-Fries rearrangement in 43% yield. 7,7'-Bis(diethylamino-carbonyloxy)-6,6'-diiodo-8,8´-biquinolyl...
Aromatic heterocycles are core structural motifs in natural products, pharmaceuticals and biological polymers. Indoles, in particular, represent a significant subclass of aromatic heterocycles, both in terms of sheer numbers, but also in biological and pharmaceutical relevance. As such, new methodologies for the synthesis of indoles represent an important and continually...
Ambifunctional axially chiral 2,2',6,6'-tetrasubstituted biphenyls containing nucleophilic (or basic) functional groups juxtaposed with hydrogen-bond donors were synthesized and their properties studied. Applications for the prepared biaryls as potential organocatalysts for enantioselective carbon-carbon bond forming reactions were examined. Processes investigated included: aldol, Michael, nitroaldol (Henry), and Baylis-Hillman reactions.
The novel amidoamine...