The F13L protein is the major envelope antigen of vaccinia virus, the prototypic member of the Orthopoxvirus genus. F13L is 372 residues in length and is essential for the formation of wrapped forms of virus. F13L contains a number of potential functional domains including a palmitylation site, a phospholipase domain...
An inducible, mutant virus, designated vvtetO:I7L/G1L, was used to study the morphogenic proteolysis step of the vaccinia virus life cycle. The vvtetO:I7L/G1L controlled the expression of two genes, I7L, a cysteine proteinase, and G1L, a putative metalloproteinase. These proteins are involved in the maturation of viral core proteins, p4a, p4b,...
Vaccinia virus (VV) is a large double-stranded DNA virus that is a prototypic member of the orthopoxvirus family. Previous works has showed that three of the major structural proteins found within the mature VV virion core 4a, 4b, and 25K are produced from higher molecular weight precursors at late times...
Electrochemical capacitors and batteries are two major electrochemical energy storage technologies, which have been investigated extensively to meet the rapidly-growing demand for higher energy, higher power, lower cost and enhanced safety in the past few decades. With the charge storage mechanism of electrostatic charge adsorption desorption via electrical double layers,...
Personal health monitoring tools, a subset of point-of care-diagnostics, enable more frequent testing of chronic health conditions outside of a clinic setting and can inform personalized therapy or support telehealth diagnostic capabilities. While there is evidence that regular monitoring of chronic conditions can lead to better health outcomes and lower...
Vaccinia virus is the prototypic member of the Orthopoxvirus genus. It undergoes a complex replication process where a key step in the transition from immature virion to intracellular mature virion is the cleavage of the major core protein precursors. The product of the I7L open reading frame (ORF) is a...
L1R, a myristylated late gene product of vaccinia virus, is essential for formation of infectious intracellular mature virions (IMV). In its absence, only viral particles arrested at an immature stage are detected and no infectious progeny virus are produced. Previous studies have shown that the L1R protein is exclusively associated...
A significant challenge for energy storage technologies is to realize battery-level energy density and capacitor-level durability and
power density in one device. By introducing an electrolyte composed of an anionic catholyte and a cationic anolyte into a symmetric
carbon-based supercapacitor configuration, a hybrid electrochemical battery-supercapacitor system using soluble redox species...
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, and R. S. Ruoff,
Science, 332, 1537 (2011).
15. M. F. El-Kady, V. Strong, S. Dubin, and R. B. Kaner
Converting CO2 to valuable materials is attractive.Herein, we report using simple metallothermic reactions to reduce atmospheric CO2 to dense nanoporous graphene. By using a Zn/Mg mixture as a reductant, the resulted nanoporous graphene exhibits highly desirable properties: high specific surface area of 1900 m2/g, a great conductivity of 1050 S/m...
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desirable
properties: high specific surface area of 1900 m2/g, a great conductivity of 1050 S/m and a tap
Current detection methods for bacterial contamination rely on structure based detection of proteins and nucleic acids. While these methods are easy to use and reliable, they cannot evaluate the toxicity of a sample and the potential to cause disease. Previously, erythrophore cells derived from Betta splendens had been suggested as...