The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are known as molecular ‘light-switches’ for DNA. This property is poised to serve in diagnostic and therapeutic applications, but the poor cellular uptake restricts their use in live cells. Herein, we show that the cellular uptake, and more interestingly and surprisingly, the nuclear...
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-Juan Chao, Chun-HuaHuang and Yan Li
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The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are known as molecular ‘light-switches’ for DNA. This property is poised to serve in diagnostic and therapeutic applications, but the poor cellular uptake restricts their use in live cells. Herein, we show that the cellular uptake, and more interestingly and surprisingly, the nuclear...
Full Text:
Chun-Hua Huanga and Yan Lia
The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are
The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are known as molecular ‘light-switches’ for DNA. This property is poised to serve in diagnostic and therapeutic applications, but the poor cellular uptake restricts their use in live cells. Herein, we show that the cellular uptake, and more interestingly and surprisingly, the nuclear...
The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are known as molecular ‘light-switches’ for DNA. This property is poised to serve in diagnostic and therapeutic applications, but the poor cellular uptake restricts their use in live cells. Herein, we show that the cellular uptake, and more interestingly and surprisingly, the nuclear...
Simultaneous translation, which translates concurrently with the source language speech, is widely used in many scenarios including multilateral organizations. However, it is well known to be one of the most challenging tasks for humans due to the simultaneous perception and production in two languages. On the other hand, simultaneous translation...
Dyphylline is an analogue of theophylline and the
latter is the most popular member of the methyixanthine
family in use for the treatment of asthma. Although
dyphylline is devoid of some problems associated with
theophylline, a reported short half-life for dyphylline
(2.1 hours) has made its clinical usefulness limited. In...
Dyphylline is an analog of theophylline and the latter
is the most popular member of the methylxanthine family in
use for the treatment of asthma. Although dyphylline is
devoid of some problems associated with theophylline, a
reported short half-life has made it's clinical usefulness
limited. To avoid this problem a...
A study of deep levels of the emitter region of a
heterojunction bipolar transistor is investigated using deep
level transient spectroscopy (DLTS), deep level admittance
spectroscopy (DLAS), thermally stimulated capacitance
(TSCAP), and capacitance-voltage (C-V) profiling. The DX
center, with an activation energy of 0.45 eV, is the only
deep level...
Simultaneous speech translation (SimulST) is widely useful in many cross-lingual communication scenarios, including multinational conferences and international traveling. Since text-based simultaneous machine translation (SimulMT) has achieved great success in recent years. The conventional cascaded approach for SimulST uses a pipeline of streaming ASR followed by simultaneous MT but suffers from...
RNAs play important roles in multiple cellular processes, and many of their functions rely on folding to specific structures. To maintain their functions, secondary structures of RNA homologs are conserved across evolution. These conserved structures provide critical targets for diagnostics and therapeutics. Thus, there is a need for developing fast...