The AhR is a ligand-activated transcription factor that mediates the potent immunosuppressive effects of TCDD. AhR-dependent changes in gene expression appear to alter the differentiation of CD4+ T cells to induce a population of CD4+CD25+ T regulatory cells (Tregs) that suppress the immune response. Ascertaining if and how the AhR...
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Receptor (AhR)
Method Development in In Vitro Immune Response
JacobHuber
Dept. of Environmental and
The AhR is a ligand-activated transcription factor that mediates the potent immunosuppressive effects of TCDD. AhR-dependent changes in gene expression appear to alter the differentiation of CD4+ T cells to induce a population of CD4+CD25+ T regulatory cells (Tregs) that suppress the immune response. Ascertaining if and how the AhR...
Full Text:
ABSTRACT OF THE THESIS OF
JacobHuber for the degree of Baccalaureate of Science in Bioresource Research
The AhR is a ligand-activated transcription factor that mediates the potent immunosuppressive effects of TCDD. AhR-dependent changes in gene expression appear to alter the differentiation of CD4+ T cells to induce a population of CD4+CD25+ T regulatory cells (Tregs) that suppress the immune response. Ascertaining if and how the AhR...
This study examined changes in flour functionality during storage of grain and subsequent aging of flour milled from the grain. Freshly harvested grain was stored for 24 weeks and flour milled from the grain at specified time intervals after harvest (0, 3, 6, 12, and 24 weeks). For each milling...
With Alzheimer’s disease being the most prominent form of dementia, finding potential treatments for the disease is imperative. This study explored the non-steroidal anti-inflammatory drug ibuprofen as a potential treatment to normalize the hyperactive N-methyl-d-aspartate receptor (NMDAR) within the 5xFAD mice early in the disease pathology before cognitive decline. Female...
Additive manufacturing has become a promising method for the fabrication of inexpensive, green, flexible sensors and electronics. Printed electronics on low- temperature substrates are very appealing for the flexible hybrid electronics market for their use in disposable and biocompatible electronic applications and in areas like packaging, wearables, and consumer electronics....
This work investigates the in-tube condensation of low global warming potential (GWP) zeotropic refrigerant mixtures R448A, R450A, R452A, R454B and R454C. These refrigerants have been proposed for a wide range of commercial heating, ventilation, air-conditioning applications, but their heat and momentum transport phenomenon were not well understood. Thus, in this...
This article investigates the in-tube, superheated, saturated, and subcooled condensation of zeotropic refrigerant mixture R454C. R454C is proposed to replace R404A for commercial refrigeration applications. Quasi-local heat transfer coefficients were measured in a 4.7 mm horizontal tube at mass fluxes ranging from 100 to 500 kg m−2 s−1 at three different saturation...
The objective of this paper was to measure and compare the heat transfer coefficient and pressure drop of R404A and two potential replacement candidate refrigerants with a lower global warming potential, R448A and R452A. Experiments were conducted inside a 4.7 mm horizontal tube at mass fluxes ranging from 100 to...
Heat transfer coefficients and frictional pressure drop values are experimentally measured during condensation of R134a and its proposed low global warming potential (GWP) replacement, R450A. R450A is a non-flammable zeotropic mixture of R134a and R1234ze (42/58% by mass). Experiments were conducted in a horizontal tube (ID = 4.7 mm) for...