Intravenous regional limb perfusion (IVRLP) with tiludronate is a commonly used treatment for distal limb orthopedic disease in horses, but doses and protocols are anecdotal. IVRLP exposes articular cartilage within the perfused area to tiludronate, raising concerns about safety of this treatment, as high tiludronate concentrations (≥19mg/L) were harmful for...
Anecdotal accounts of tiludronate administration via intravenous regional limb
perfusion (IVRLP) exist despite a lack of information regarding safety for synovial
structures in the perfused area. The objective of this study was to determine whether
tiludronate concentrations in synovial structures after IVRLP with low dose (0.5 mg,
LDT) or high...
Full Text:
Interests
The authors declare there are no competing interests.
Author Contributions
• BarbaraG. Hunter
Anecdotal accounts of tiludronate administration via intravenous regional limb
perfusion (IVRLP) exist despite a lack of information regarding safety for synovial
structures in the perfused area. The objective of this study was to determine whether
tiludronate concentrations in synovial structures after IVRLP with low dose (0.5 mg,
LDT) or high...
Full Text:
Knotty T4 low dose Treatment Key TP total synovial fluid protein in g/dl
7 Max T5 high dose horse name
Anecdotal accounts of tiludronate administration via intravenous regional limb perfusion (IVRLP) exist despite a lack of information regarding safety for synovial structures in the perfused area. The objective of this study was to determine whether tiludronate concentrations in synovial structures after IVRLP with low dose (0.5 mg, LDT) or high...
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As IAMSLIC members will recall, in 1990 Stephanie Haas questioned ASFA’s supremacy in marine science libraries and found “potential pitfalls” if relying on a single database to adequately discover the relevant literature (Haas 1990). We still question the best way to access the literature in our multidisciplinary field. Patrons and...
As IAMSLIC members will recall, in 1990 Stephanie Haas questioned ASFA’s supremacy in marine science libraries and found “potential pitfalls” if relying on a single database to adequately discover the relevant literature (Haas 1990). We still question the best way to access the literature in our multidisciplinary field. Patrons and...
As IAMSLIC members will recall, in 1990 Stephanie Haas questioned ASFA’s supremacy in marine science libraries and found “potential pitfalls” if relying on a single database to adequately discover the relevant literature (Haas 1990). We still question the best way to access the literature in our multidisciplinary field. Patrons and...