The induction of drug-metabolizing enzymes is a
complex biochemical process manifested not only by
increases in various cytochrome P-450 isozymes and
related activities, but also by alterations in
endoplasmic reticulum membranes. Little work has been
done to examine how cytochrome P-450 inducing agents
influence other cellular processes, such as
Aquatic animals are exposed to a variety of natural and
anthropogenic xenobiotics. Biotransformation of xenobiotics was
examined in three aquatic animals: a primitive mollusc (chiton);
a shellfish which is an important human food source (oyster);
and, a lower vertebrate model for toxicological studies (rainbow
trout). Since digestive glands of Cryntochiton...
Celebrity culture is part of a long history of fame, but the modern celebrity individual came into focus in the nineteenth century. The first part of this thesis distinguishes modern celebrity – including its morality – from other types of fame, explores the intersection of celebrity and gender through the...
Seismic refraction data collected in 1985 by the USGS were used in
this study to derive the P and S velocity structure of the crust beneath the
Gulf of Maine. The data quality differs among instruments and is affected
by surficial lateral heterogeneities, a ringy source signature and
Seabirds are an integral component of marine ecosystems, however, because humans typically observe only snapshots of their lives at sea, our understanding of seabird foraging ecology is often limited. A more complete understanding of the ecological roles of seabirds and identification of critical foraging habitats requires the ability to follow...
Greater degrees of insulin resistance are associated with increased rates of
coronary artery disease (CAD) progression. However, the specific behavioral
determinants of insulin resistance are not well known in patients with CAD. Although
abdominal obesity contributes to insulin resistance, the extent to which abdominal obesity
may modify the relationship between...