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KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures.pdf

Creator:: Driggers, Camden M., Cooley, Richard B., Sankaran, Banumathi, Hirschberger, Lawrence L., Stipanuk, Martha H., and Karplus, P. Andrew
Abstract:: Mammalian cysteine dioxygenase (CDO) is a mononuclear non-heme iron protein that catalyzes 2 the conversion of cysteine (Cys) to cysteine sulfinic acid (CSA) by an unclarified mechanism. 3 One structural study revealed a Cys-persulfenate (or Cys-persulfenic acid) formed in the active 4 site, but quantum mechanical calculations have been used...
Full Text:: 15 the Berkeley Center for Structural Biology supported in part by the National Institutes of

The circadian clock gene period extends healthspan in aging Drosophila melanogaster

Creator:: Krishnan, Natraj, Kretzchmar, Doris, Rakshit, Kuntol, Chow, Eileen, and Giebultowicz, Jadwiga M.
Abstract:: There is increasing evidence that aging is affected by biological (circadian) clocks – the internal mechanisms that coordinate daily changes in gene expression, physiological functions and behavior with external day/night cycles. Recent data suggest that disruption of the mammalian circadian clock results in accelerated aging and increased age‐related pathologies such...
Resource Type:: Article
Full Text:: . Green CB, Takahashi JS, Bass J. The meter of metabolism. Cell. 2008; 134:728‐742. 3. Huang YL, Liu RY

Modeling Sources of Teaching Self-Efficacy for Science, Technology, Engineering, and Mathematics Graduate Teaching Assistants

Creator:: DeChenne, Sue Ellen, Koziol, Natalie, Needham, Mark, and Enochs, Larry
Abstract:: Graduate teaching assistants (GTAs) in science, technology, engineering, and mathematics (STEM) have a large impact on undergraduate instruction but are often poorly prepared to teach. Teaching self-efficacy, an instructor’s belief in his or her ability to teach specific student populations a specific subject, is an important predictor of teaching skill...
Resource Type:: Article

Modeling Sources of Teaching Self-Efficacy for Science, Technology, Engineering, and Mathematics Graduate Teaching Assistants

Creator:: DeChenne, Sue Ellen, Koziol, Natalie, Needham, Mark, and Enochs, Larry
Abstract:: Graduate teaching assistants (GTAs) in science, technology, engineering, and mathematics (STEM) have a large impact on undergraduate instruction but are often poorly prepared to teach. Teaching self-efficacy, an instructor’s belief in his or her ability to teach specific student populations a specific subject, is an important predictor of teaching skill...
Resource Type:: Article

Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function

Creator:: He, Yue, Yam, Candice, Pomraning, Kyle, Chin, Jacqueline S. R., Yew, Joanne Y., Freitag, Michael, and Oliferenko, Snezhana
Abstract:: Excess fatty acids and sterols are stored as triacylglycerols and sterol esters in specialized cellular organelles, called lipid droplets. Understanding what determines the cellular amount of neutral lipids and their packaging into lipid droplets is of fundamental and applied interest. Using two species of fission yeast, we show that cycling...
Resource Type:: Article
Full Text:: function. Molecular Biology of the Cell, 25(25), 4083-4095. doi:10.1091/mbc.E14-03-0832 10.1091/mbc.E14

The Neurospora crassa exocyst complex tethers Spitzenkörper vesicles to the apical plasma membrane during polarized growth

Creator:: Riquelme, Meritxell, Bredeweg, Erin L., Callejas-Negrete, Olga, Roberson, Robert W., Ludwig, Sarah, Beltrán-Aguilar, Alejandro, Seiler, Stephan, Novick, Peter, and Freitag, Michael
Abstract:: Fungal hyphae are among the most highly polarized cells. Hyphal polarized growth is supported by tip-directed transport of secretory vesicles, which accumulate temporarily in a stratified manner in an apical vesicle cluster, the Spitzenkörper. The exocyst complex is required for tethering of secretory vesicles to the apical plasma membrane. We...
Resource Type:: Article

Cysteine dioxygenase structures from pH 4 to 9: consistent Cys-persulfenate formation at intermediate pH and a Cys-bound enzyme at higher pH

Creator:: Driggers, Camden M., Cooley, Richard B., Sankaran, Banumathi, Hirschberger, Lawrence L., Stipanuk, Martha H., and Karplus, P. Andrew
Abstract:: Mammalian cysteine dioxygenase (CDO) is a mononuclear non-heme iron protein that catalyzes 2 the conversion of cysteine (Cys) to cysteine sulfinic acid (CSA) by an unclarified mechanism. 3 One structural study revealed a Cys-persulfenate (or Cys-persulfenic acid) formed in the active 4 site, but quantum mechanical calculations have been used...
Resource Type:: Article

KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures(SupplementaryInformation).pdf

Creator:: Driggers, Camden M., Cooley, Richard B., Sankaran, Banumathi, Hirschberger, Lawrence L., Stipanuk, Martha H., and Karplus, P. Andrew
Abstract:: Mammalian cysteine dioxygenase (CDO) is a mononuclear non-heme iron protein that catalyzes 2 the conversion of cysteine (Cys) to cysteine sulfinic acid (CSA) by an unclarified mechanism. 3 One structural study revealed a Cys-persulfenate (or Cys-persulfenic acid) formed in the active 4 site, but quantum mechanical calculations have been used...
Full Text:: is weaker than that of the Cys93 Sγ, consistent with the iron having 5 decreased occupancy. We

Evidence for geomagnetic imprinting as a homing mechanism in Pacific salmon

Creator:: Putnam, Nathan F., Lohmann, Kenneth J., Putnam, Emily M., Quinn, Thomas P., Klimley, A. Peter, and Noakes, David L. G.
Abstract:: In the final phase of their spawning migration, Pacific salmon use chemical cues to identify their home river, but how they navigate from the open ocean to the correct coastal area has remained enigmatic [1]. To test the hypothesis that salmon imprint on the magnetic field that exists where they...
Resource Type:: Article
Full Text:: animals: nature’s GPS. Journal of Experimental Biology 210, 3697-3705. 11. Quinn, T.P. (1980). Evidence

Menage a trois : an evolutionary interplay between human papilloma virus, a tumor and a woman

Creator:: Shulzhenko, Natalia, Lyng, Heidi, Sanson, Gerdine F., and Morgun, Andrey
Abstract:: Cervical cancer is the third most common cancer in women with Human papillomavirus (HPV) being a key etiologic factor of this devastating disease. In this article, we describe modern advances in the genomics and transcriptomics of cervical cancer that led to uncovering the key gene drivers. We also introduce, herein,...
Resource Type:: Article
Full Text:: 31b in cell lines containing viral episomes. Journal of virology 66, 6070- 6080 14 Cheng, S., et al

ScholarsArchive@OSU

KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures.pdf

The circadian clock gene period extends healthspan in aging Drosophila melanogaster

Modeling Sources of Teaching Self-Efficacy for Science, Technology, Engineering, and Mathematics Graduate Teaching Assistants

Modeling Sources of Teaching Self-Efficacy for Science, Technology, Engineering, and Mathematics Graduate Teaching Assistants

Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function

The Neurospora crassa exocyst complex tethers Spitzenkörper vesicles to the apical plasma membrane during polarized growth

Cysteine dioxygenase structures from pH 4 to 9: consistent Cys-persulfenate formation at intermediate pH and a Cys-bound enzyme at higher pH

KarplusPAndrewBiochemistryBiophysicsCysteineDioxygenaseStructures(SupplementaryInformation).pdf

Evidence for geomagnetic imprinting as a homing mechanism in Pacific salmon

Menage a trois : an evolutionary interplay between human papilloma virus, a tumor and a woman

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