Index Catalog // ScholarsArchive@OSU

Acute bioactivation and hepatotoxicity of ketoconazole in rat and the determinant presence of flavin-containing monooxygenase (FMO) isoforms in human duodenum, jejunum, ileum, and colon microsomes and Caco-2 cell line

Creator:: Buckholz, Cheryl J.
Abstract:: Two specific goals were addressed for this dissertation. First to investigate and identify the mechanistic profile of ketoconazole (KT)-induced hepatotoxicity by utilizing in vivo and in vitro approaches determining the mechanism of action for the hepatotoxicity incurred. To date, there has not been a mechanistic determination of the hepatotoxicity associated...
Resource Type:: Dissertation
Full Text:: Hepatotoxicity of Ketoconazole in Rat and the Determinant Presence of Flavin-containing Monooxygenase (FMO

The effect of concentration on the toxicity of chemicals to living organisms

Creator:: Bateman, Ernest
Resource Type:: Technical Report
Full Text:: diagrammatically in Figure 4 ; they show that air is an essentia l factor in toxicity testing . The largest Petri

The determination of the relative toxicity of several fractions of coal tar creosote on wood destroying fungi

Creator:: Berselli, Bruno
Resource Type:: Undergraduate Thesis
Full Text:: The determination of the relative toxicity of several

Quantitative determination of emerging contaminants, solvent stabilizers and fullerene nanomaterials, in biological and environmental systems

Creator:: Isaacson, Carl W.
Abstract:: To determine the impact of emerging environmental contaminants on human and environmental health, quantitative analytical methods are required. Analysis of emerging contaminants is hampered by their widely varying physical-chemical properties. Therefore quantitative analytical methods must be developed to determine the behavior of emerging contaminants in environmental systems. A quantitative analytical...
Resource Type:: Dissertation
Full Text:: . QUANTIFICATION OF FULLERES BY LC/ESI-MS AND ITS APPLICATION TO IN VIVO TOXICITY ASSAYS................ 82

Assessing the Impacts of Size, Structure, and Surface Chemistry on the Toxicity of Two High Production Organic Nanomaterials using the Embryonic Zebrafish Model

Creator:: Meredith, Ailcea N.
Abstract:: The low risk and sustainable implementation of nanotechnology requires understanding how nanomaterial physicochemical properties influence their toxicity. Major drivers of toxicity need to be avoided while maximizing product efficacy so nanomaterials can be produced to best serve their applications and be of low risk when intentionally or unintentionally released into...
Resource Type:: Masters Thesis
Full Text:: (Dooley 2000). Information gathered from toxicity testing with zebrafish helps to inform both human and

Process segmentation and modelling applied to time series featuring the response of biological materials to toxic agents

Creator:: Teng, Angela
Abstract:: The detection of biological and chemical toxins has become one of the main concerns in environmental and military fields. In this framework, the department of Microbiology and Biochemistry at Oregon State University has discovered that fish living cells are promising indicators of the presence of a wide range of toxins....
Resource Type:: Masters Thesis

Some toxicity data and their practical significance

Creator:: Bateman, Ernest, Baechler, Roy H., and Forest Products Laboratory (U.S.)
Abstract:: Information reviewed and reaffirmed June, 1959. Date of original report January 19, 1937.
Resource Type:: Technical Report
Full Text:: .SD Li33 • a SOME TOXICITY DATA AND THEIR PRACTICAL SIGNIFICANCE

Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Creator:: Haggard, Derik
Abstract:: There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...
Resource Type:: Dissertation
Full Text:: realize the vision of 21st century toxicity testing. In this dissertation, I employed transcriptomics

Toxicity of Fungal Pigments from Chlorociboria spp. and Scytalidium spp.

Creator:: Almurshidi, Badria H.
Abstract:: Commercial methodologies for producing fungal pigments are of worldwide interest due to the desire to move away from synthetic dyes. Chlorociboria species and Scytalidium species have been reported to produce sufficient yields of pigments for commercial production and have attracted special attention because of their use in spalted wood applications....
Resource Type:: Masters Thesis
Full Text:: models for ecotoxicology and acute toxicity testing although advancements have been made in the field

Functionalization of carbon nanotubes for effective biosensing and potential biomedical applications

Creator:: Adenuga, Adeniyi A.
Abstract:: Since their discovery in the 1990s, the great potential of carbon nanotubes (CNTs) has made them a focus of many research endeavors, including their application as components of biosensors. The inherent chemical "inertness" of CNTs makes their application to biosensing a challenge. It is necessary to "decorate" their surfaces to...
Resource Type:: Dissertation
Full Text:: ................................................................................................... 125 4.3.4. Toxicity testing

ScholarsArchive@OSU

Acute bioactivation and hepatotoxicity of ketoconazole in rat and the determinant presence of flavin-containing monooxygenase (FMO) isoforms in human duodenum, jejunum, ileum, and colon microsomes and Caco-2 cell line

The effect of concentration on the toxicity of chemicals to living organisms

The determination of the relative toxicity of several fractions of coal tar creosote on wood destroying fungi

Quantitative determination of emerging contaminants, solvent stabilizers and fullerene nanomaterials, in biological and environmental systems

Assessing the Impacts of Size, Structure, and Surface Chemistry on the Toxicity of Two High Production Organic Nanomaterials using the Embryonic Zebrafish Model

Process segmentation and modelling applied to time series featuring the response of biological materials to toxic agents

Some toxicity data and their practical significance

Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Toxicity of Fungal Pigments from Chlorociboria spp. and Scytalidium spp.

Functionalization of carbon nanotubes for effective biosensing and potential biomedical applications

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