Alaska pollock (Gadus chalcogrammus) is a schooling whitefish native to the Bering Sea that is prized for its fillets, surimi, roe, and milt. Fillets are frequently used for popular products such as fish and chips. If collected, roe and milt are commonly exported to South Korea and Japan. However, no...
Glycomacropeptide (GMP) is a bioactive peptide found in the dairy product whey, along with whey protein isolate (WPI). Past studies have shown that digested GMP retains bioactivity in rodent guts. This study tested whether GMP or GMP-derived peptides or whey protein or whey protein-derived peptides inhibit pro-inflammatory cytokines. THP-1 cells...
Ewing sarcoma (EwS) is the second most highly malignant tumor that arises mainly from bone and surrounding soft tissue of adolescent and young adult patients. Despite the advances in Ewing sarcoma treatment that today include a combination of five chemotherapeutic agents, surgery, and/or radiotherapy, these therapies have demonstrated limited improvement...
Objective: Red raspberries are rich in polyphenols and fiber, relatively low in sugar compared with other fruits, and have been demonstrated to have favorable effects on energy homeostasis in mice. However, it has been unclear precisely which compounds within red raspberries possess the greatest bioactivity, and their mechanism of action....
In biological systems, antioxidants are bioactive compounds that protect against oxidation of lipids, proteins, and DNA. Natural antioxidant peptides are often purified and isolated from proteins as a less toxic alternative to synthetic peptides, but the mechanisms behind their activity are not well understood. The purpose of this study is...
Polyphenolic compounds found in foods such as fruits, vegetables, legumes, nuts and grains, are an integral part of the human diet. Within polyphenols, proanthocyanidins are referred to as condensed tannins and encompass procyanidins, propelargonidins and prodelphinidins. Among these, procyanidins are the largest group. Recent interest in these compounds is related...