Index Catalog // ScholarsArchive@OSU

Creator:: Dien, Thalia
Abstract:: Background Feline injection-site sarcoma (FISS) is a rare and aggressive tumor associated with vaccines, drug injections, and skin trauma in cats. The understanding of FISS remains limited, posing challenges in its diagnosis, treatment, and prevention. In this study, we analyzed the differential expression of miRNAs and their target genes in...
Resource Type:: Undergraduate Thesis
Full Text:: _____________________________________________________ Christiane Löhr, Carlson College of Veterinary Medicine

Creator:: Kiefel, Claire A.
Abstract:: Gonadectomy has been associated with a 1.5-2 fold increase in the occurrence of canine hip dysplasia and a 2-3 fold increase in the occurrence of canine anterior cruciate ligament (ACL) injury. In intact dogs, luteinizing hormone (LH) is secreted from the adenohypophysis to stimulate the synthesis of gonadal hormones, which...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Christiane Löhr, Committee Member, representing Biomedical Sciences

Creator:: Trummel, Danielle K.
Abstract:: Mammary tumors are the third most common tumor in cats after cutaneous neoplasia and lymphosarcoma. More than 80% of feline mammary tumors are adenocarcinomas, which are similar to human mammary adenocarcinomas in their biologic behavior and histologic characteristics. Despite treatment with radical mastectomy, feline mammary adenocarcinoma is associated with a...
Resource Type:: Undergraduate Thesis and Presentation
Full Text:: ________________________________________________________________________ Tertiary Mentor: Dr. Christiane Lohr Date

Creator:: Chagani, Sharmeen
Abstract:: Cutaneous melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment-producing melanocytes, with a diagnosis of metastasis indicating a median survival rate of less than a year. Solar ultraviolet (UV) radiation, especially childhood sun exposure, is an important etiological risk factor of melanoma. This DNA damage...
Resource Type:: Dissertation
Full Text:: Carpenter (analysis of imaging data), Dr. Christiane V. Löhr (pathological assessments of histological

Creator:: Madeen, Erin
Abstract:: The objective of this work is to add to the body of translational data between high dose animal model research and the environmentally relevant human metabolism of the persistent pollutant dibenzo[def,p]chrysene (DBC). We furthered the knowledge of gene/exposure interactions by determining the carcinogenesis risk based on Cyp1b1 genotype following in...
Resource Type:: Dissertation
Full Text:: toxicology training were provided by Drs. Christiane Löhr and Ulrike Luderer, both of whom have spent

Creator:: Hughes, Kelly L.
Abstract:: The endogenous circadian clock is an intracellular transcriptional feedback loop timing daily patterns of multiple biological rhythms within a 24-hour period. Disturbance in various rhythms leads to alteration of normal biological processes including cellular proliferation and tumor suppression. Endogenous circadian clock rhythms have been found to be disrupted in breast...
Resource Type:: Masters Thesis

Creator:: Paquette, Colleen Elizabeth
Abstract:: Zebrafish (Danio rerio) have become an increasingly important model organism for cancer research. There are several cancer models in which neoplasms are induced chemically or genetically. However, spontaneous (unknown etiology) neoplasms are rather common in zebrafish, particularly in older fish. For over a decade, spontaneous intestinal neoplasia and preneoplastic intestinal...
Resource Type:: Masters Thesis
Full Text:: . Peterson assisted with the histological interpretation of hundreds of zebrafish specimens Christiane V

Creator:: Peterson, Tracy Shawn
Abstract:: Mycobacteriosis is a common disease of laboratory zebrafish (Danio rerio). Different infection patterns occur in zebrafish depending on mycobacterial species. Mycobacterium marinum and M. haemophilum produce virulent infections associated with high mortality, whereas M. chelonae is more wide spread and not associated with high mortality. Identification of mycobacterial infections to...
Resource Type:: Dissertation
Full Text:: my committee for their service and contributions to my work: Jerry Heidel, Christiane Löhr, Bruce

ScholarsArchive@OSU