The context of this thesis is a research project focused on the investigation of a renewable biopolymer-poly(lactic acid) (PLA) as a potential replacement of petroleum-based polymers in advanced nanocomposites reinforced with Microfibrillated cellulose (MFC). MFC is extracted from wood, which is a renewable, sustainable, carbon neutral and recyclable material. This...
Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
Designing spectral efficient, high-speed wireless links that offer high quality-
of-service and range capability has been a critical research and engineering challenge. In this thesis, we mainly address the complexity and performance issues of
channel estimation and data detection in multiple-input multiple-output (MIMO)
orthogonal frequency division multiplexing (OFDM) systems over...
Parallel loops are one of the main sources of parallelism in scientific applications, and many parallel loops do not have a uniform iteration execution time. To achieve good performance for such applications on a parallel computer, iterations of a parallel loop have to be assigned to processors in such a...
Physical activity is important for health. However, there is a lack of literature related to the physical activity levels of adults living in urban villagers, which is a vulnerable population in China. The aim of this study is to compare the physical activity and sedentary behavior engagements between urban villagers...
Small RNAs, including microRNAs (miRNAs), small interfering RNAs
(siRNAs), and trans-acting siRNAs (tasiRNAs), control gene expression
and epigenetic regulation. Although the roles of miRNAs and
siRNAs have been extensively studied, their expression diversity
and evolution in closely related species and interspecific hybrids
are poorly understood. Here, we show comprehensive analyses...
Abstract: Background: Chronic exposure to arsenic in drinking water is associated with increased risk of type 2 diabetes mellitus (T2DM) but the underlying molecular mechanism remains unclear.
Objectives: This study evaluated the interaction between single nucleotide polymorphisms (SNPs) in genes associated with diabetes and arsenic exposure in drinking water on...
Emerging evidence suggests that the tumor microenvironment plays a critical role in regulating cancer
stem cells (CSCs) and tumor progression through both autocrine and paracrine signaling. Elevated
production of bone morphogenetic proteins (BMPs) from human ovarian cancer cells and stroma has
been shown to increase CSC proliferation and tumor growth....
Vitamin E (VitE) is necessary for vertebrate embryonic development. VitE prevents lipid peroxidation (LPO), which requires detoxification by cellular antioxidant systems subsequently involving reducing power derived from energy metabolism. Thus, VitE protects metabolic networks in the developing embryo and the integrated gene expression networks compensating for and impaired by LPO-induced...
Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
Full Text:
, Han-Ming Wang
8
, Jie Dong
8
, Gu-Yan Zheng
8
, Li Lin
5
, Feng Qian
5
, Yanwei
Qi
3,9
, Xiao