Introduction. Painful diabetic peripheral neuropathy (DPN) is a common complication of diabetes that interferes with daily living and causes severe pain. Pharmacotherapy is the accepted treatment strategy, however, this strategy is associated with high cost, minimal reductions in pain, and adverse side effects. Thus, a critical need exists to develop...
Introduction: A bone deficit is found to persist five years following a hip fracture and 10 years post tibial fracture in adults. We examined the effect of whole body vibration (Vib) as a means for enhancing whole body composition and bone recovery following hindlimb unloading (HU) of adult female rats....
Exercise-related menstrual dysfunction (ExMD) is associated with low energy availability (EA), decreased bone mineral density (BMD), and increased risk of musculoskeletal injury. We investigated whether a 6-month carbohydrate-protein (CHO-PRO) supplement (360 kcal/day, 54 g CHO/day, 20 g PRO/day) intervention would improve energy status and musculoskeletal health and restore menses in...
Aging, obesity and increased waist circumference (WC) increases risk for metabolic syndrome (MetS). MetS is a cluster of symptoms (elevated WC, triglycerides, blood pressure, fasting glucose, and decreased high-density lipoprotein cholesterol [HDL-C]) increasing risk for chronic disease. Low-energy dense (LED) diets, emphasizing whole food eating patterns, have not been examined...
Background: Alcohol is a nonessential nutrient widely consumed throughout the world. Chronic alcohol abuse is associated with numerous adverse skeletal effects. However, prior to this study, the effects of alcohol abuse on intracortical bone remodeling in an animal model had not been investigated. Reduced intracortical bone remodeling could impair repair...
Epidemiological studies have reported that postmenopausal women who consume moderate quantities of alcohol have higher bone mass than non-drinkers. However, the mechanism for the putative bone-sparing effect of alcohol is unknown. Postmenopausal bone loss is due, in part, to increased bone turnover. This study investigated the hypotheses that alcohol slows...
Postmenopausat women on hormone replacement therapy (HRT) have been reported to be stronger when compared to women who are not using HRT. The first goal of this study was to investigate whether muscle morphology was altered in women who use HRT when compared to women who do not use HAT....
We investigated the relationship between calcium and protein intake and bone loss over a one-year period in 99 early postmenopausal women (1-36 months) aged 51.3 ± 0.31 years. Bone mineral density (g/cm²) of the left hip (total hip, femoral neck, greater trochanter) and lumbar spine (L1-L4) as well as body...
Research shows that Exercise-Associated Menstrual Dysfunction (ExMD) ranges from 6-79% of active women, depending on the sport. The primary contributor to ExMD is hypothesized to be low energy availability or relative energy deficiency in sport, due to insufficient energy intake to match exercise energy expenditure. Because many active women are...