Background: Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA/RNA analogs that silence expression of specific genes. We studied whether PPMOs targeted to essential genes in Acinetobacter lwoffii and A. baumannii are active in vitro and in vivo. Methods: PPMOs were evaluated in vitro using MIC and viability assays, and in...
In this thesis, I discuss the uses of two different forms of young adult novels for relaying messages about adolescence and femininity to adolescents from adult authors. I explore the traditional and organized quest narrative as written by Anne McCaffrey in her Harper Hall Trilogy with a young female hero....
The purpose of this study was to determine if personality
traits relevant to creativity in adults are measurable in four year
old nursery school children. Instruments and scoring techniques
were developed to measure six specific traits. These traits are
the intellectual aptitude abilities of figural fluency, elaboration,
originality and penetration...
Ninety-five oriented samples were obtained from nine Recent
Cascade lava flows in Oregon. Directions and intensities of remanent
magnetization were measured on a spinner magnetometer which measures
directions of magnetization to within 1.2° s.d. Angle measurements
were plotted graphically using an equal area projection. Mean
directions and statistics were calculated...
Nearly 9,000 feet of Cretaceous mudstones, shales, sandstone,
and conglomerates are exposed along the northeast-trending Mitchell
anticline of central Oregon, These rocks are divided into two formations
on the basis of criteria developed in this investigation. The
lower formation, hereby designated the Meyers Formation, is 4,716
feet thick at its...
Female sexual promiscuity is a prevalent element of mating systems. One consequence of female sexual promiscuity is that male‐male competition often continues post‐copulation within the female’s reproductive tract. According to theory, the number of sperm a male inseminates relative to his rivals strongly predicts his fertilization success. However, sperm quality...
As colony-specific wintering ecology of small and medium-sized seabirds is poorly understood, it has been generally assumed that winter conditions have the same effect on all individuals from any given colony. However, advances in global positioning technology now allow researchers to investigate movements of smaller seabirds. We tracked black-legged kittiwakes...
Sexual conflict over mating can result in sex specific morphologies and behaviors that
allow each sex to exert control over the outcome of reproduction. Genital traits, in
particular, are often directly involved in conflict interactions. Via genital manipulation,
we experimentally investigated whether genital traits in red-sided garter snakes influence
copulation...
High-elevation aquatic ecosystems are highly vulnerable to climate change, yet relatively few records are available to characterize shifts in ecosystem structure or their underlying mechanisms. Using a long-term data set on seven alpine lakes (3126 to 3620 m) in Colorado, USA, we show that ice-off dates have shifted 7 days earlier over...
Full Text:
Citation:
Preston, D. L., N. Caine, D. M. McKnight,
M. W. Williams, K. Hell, M. P. Miller,
S. J. Hart, and