Educational institutions are exposed to a continuously changing environment. As in business, they experiment with their methods and techniques to improve their outputs. Performance assessment, both in education and business is a gray science. It is not just a question of evaluating performance. Performance is comprised of a number of...
Subduction zone recycling of volatiles (H₂O, Cl, S, F) is controlled by the nature of subducted materials and the temperature-pressure profile of the downgoing slab. We investigate the variability in volatile and fluid-mobile trace element enrichment in the Sunda arc using melt inclusion data from Kawah Ijen and Tambora volcanoes,...
A continuous flow diffusion chamber (CFDC) was used to measure ice formation by
cloud particle residuals during the Cirrus Regional Study of Tropical Anvils and Cirrus
Layers-Florida Area Cirrus Experiment. These measurements were directed toward
determining the relative contributions of homogeneous nucleation, heterogeneous
nucleation, and secondary ice formation processes to...
An interagency project demonstrated the feasibility of integrating Federal surveys of terrestrial natural resources and offers a vision for that integration. At locations selected from forest inventory and analysis, National forest system Region 6, and national resources inventory surveys in a six-county area in Northern Oregon, experienced teams interpreted and...
The interaction of lecithin-cholesterol acyltransferase (LCAT) with apolipoprotein A-I (apoA-I) plays a critical role in highdensity lipoprotein (HDL) maturation.Wepreviously identified a highly solvent-exposed apoA-I loop domain (Leu¹⁵⁹–Leu¹⁷⁰) in nascent HDL, the so-called “solar flare” (SF) region, and proposed that it serves as an LCAT docking site (Wu, Z., Wagner, M....
The Holocene portion of the Siple Dome (Antarctica) ice core was
dated by interpreting the electrical, visual and chemical properties of the
were interpreted manually and with a computer algorithm.The algorithm
was adjusted to be consistent with atmospheric methane stratigraphic
(Greenland Ice Sheet Project 2) ice core, ¹⁰Be stratigraphic ties...
Agriculture is now facing the ‘perfect storm’ of climate change, increasing costs of fertilizer and rising food demands from a larger and wealthier human population. These factors point to a global food deficit unless the efficiency and resilience of crop production is increased. The intensification of agriculture has focused on...
Mutations in the metallo-protein Cu/Zn-superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS) in humans and an
expression level-dependent phenotype in transgenic rodents. We show that oral treatment with the therapeutic agent diacetyl-bis(4-methylthiosemicarbazonato)copper[superscript II] [Cu[superscript II](atsm)] increased the concentration of mutant SOD1 (SOD1G37R) in ALS model mice, but paradoxically improved locomotor...
Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
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Workshop
Paul D. Adams, Kathleen Aertgeerts, Cary Bauer, Jeffrey A. Bell, Helen M.
Berman, Talapady N