We report the first systems biology investigation of regulators controlling arterial plaque macrophage transcriptional
changes in response to lipid lowering in vivo in two distinct mouse models of atherosclerosis regression. Transcriptome
measurements from plaque macrophages from the Reversa mouse were integrated with measurements from an aortic
transplant-based mouse model of...
We report the first systems biology investigation of regulators controlling arterial plaque macrophage transcriptional
changes in response to lipid lowering in vivo in two distinct mouse models of atherosclerosis regression. Transcriptome
measurements from plaque macrophages from the Reversa mouse were integrated with measurements from an aortic
transplant-based mouse model of...
Full Text:
Activation of
the Wnt Signaling Pathway
Ramsey, S. A., Vengrenyuk, Y., Menon, P., Podolsky, I., Feig, J. E
We report the first systems biology investigation of regulators controlling arterial plaque macrophage transcriptional changes in response to lipid lowering in vivo in two distinct mouse models of atherosclerosis regression. Transcriptome measurements from plaque macrophages from the Reversa mouse were integrated with measurements from an aortic transplant-based mouse model of...