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  • The role of the homeodomain transcription factor Pitx2 in regulating skeletal muscle precursor migration and higher order muscle assembly

    Creator:
    Campbell, Adam L.
    Abstract:
    Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The regulatory mechanisms that control the later steps of this...
    Resource Type:
    Dissertation
    Full Text:
    , data analysis, and writing; Michael K. Gross contributed reagents, data analysis, analytic tools

  • Role of Pitx2 in regulation of cardiac remodelling

    Creator:
    Bhatt, Shachi
    Abstract:
    Background: Heart morphogenesis involves chamber formation followed by septation. Septation is the remodeling of the heart from a single channel peristaltic pump to a two channel pump with one-way valves. Several transcription factors have been implicated in the development of congenital cardiac defects. The paired-like homeodomain transcription factor Pitx2 has...
    Resource Type:
    Masters Thesis
    Full Text:
    . Special thanks to Dr. Michael Gross for his helpful tips and advice during my research and to my

  • Volume analysis and visualization

    Creator:
    Khare, Ankit
    Abstract:
    3D datasets acquire great importance in the context of medical imaging. In this thesis we survey and enhance solutions to problems inherently associated with 3D datasets-processing time,noise and visualization. Efforts include development of a tool kit to provide a multi-threaded processing platform to cut processing time, produce real time visualization...
    Resource Type:
    Masters Thesis
    Full Text:
    Ron Metoyer, Dr Michael J. Quinn and Dr Michael K. Gross for their time and inputs. TABLE OF

  • Gene networks during cardiogenesis and skeletal myogenesis

    Creator:
    Ma, Hsiao-Yen
    Abstract:
    Organismal development requires a precisely orchestrated transcriptional program to correctly deploy genetic information into the genome. This process requires sophisticated gene regulatory networks at multiple spatial and temporal levels from early embryonic development to adult physiological conditions. Molecular differences that define cell types are set up during the pattern formation...
    Resource Type:
    Dissertation
    Full Text:
    research, data analysis, and writing; Michael K. Gross contributed reagents, data analysis, and analytic

  • Transcriptional regulation of mouse epidermal permeability barrier development and homeostasis by Ctip2

    Creator:
    Wang, Zhixing
    Abstract:
    Skin is the largest organ in the body that protects the organism from environmental, chemical and physical traumas of each passing day. The protective skin epidermal permeability barrier (EPB) is formed within the exterior layers of the epidermis, which are regularly sloughed off and repopulated by movement of inner cells....
    Resource Type:
    Dissertation

  • The function of the homeobox transcription factor Pitx2 during mammalian skeletal muscle development

    Creator:
    Shih, Hung Ping
    Abstract:
    Homeodomain transcription factors control developmental processes. They pattern body formation, specify cell lineages and switch the onset of gene regulatory cascades. Pitx2, a bicoid-related homeodomain transcription factor, is asymmetrically expressed in the left lateral plate mesoderm and mesoderm-derived tissues. Pitx2 null mice are characterized by failure of body wall closure,...
    Resource Type:
    Dissertation
    Full Text:
    designed research; Hung Ping Shih performed research; Hung Ping Shih, Michael K. Gross and Chrissa Kioussi

  • Examining the role of Attention-Deficit/Hyperactivity Disorder (ADHD) in the life experiences of University Student-Athletes

    Creator:
    Smith, Shannon D.
    Abstract:
    This research investigates the role of Attention-Deficit/Hyperactivity Disorder (ADHD) in the life experiences of University Student-Athletes. This qualitative study employs a naturalistic and grounded paradigm in an effort to capture the essence of these experiences. Participants are four student-athletes from Oregon State University who play intercollegiate athletics in the Pac-10...
    Resource Type:
    Dissertation
    Full Text:
    invaluable insights and encouragement to be "creative." To Joan Gross for making time to be there and