In recent decades, there has been increased attention on human exposure to, and subsequently toxicity of, Polycyclic Aromatic Hydrocarbons (PAHs). PAHs are widespread organic pollutants and some have been shown to be toxic, carcinogenic and mutagenic. This research was focused on understanding the link between global PAH emissions and lung...
Signal transduction within and between cells is at the core of biological activity in all living systems. Signaling networks are required for regulating biological functions, including growth, development and survival. Deregulation of signaling cascades has been linked to chronic and acute diseases and disorders This thesis focuses on mass spectrometry...
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Motorykin for the degree of Doctor of Philosophy in Chemistry presented on
April 17 2015.
Title: Mass
One expectation of community-based participatory research (CBPR) is participant access to study results. However, reporting experimental data produced by studies involving biological measurements in the absence of clinical relevance can be challenging to scientists and participants. We applied best practices in data sharing to report the results of a study...
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Frey
1,2
, Molly L. Kile
1,2
, Barbara Harper
1,2,
, Stuart Harris
5
, OleksiiMotorykin
4
One expectation of community-based participatory research (CBPR) is participant access to study results. However, reporting experimental data produced by studies involving biological measurements in the absence of clinical relevance can be challenging to scientists and participants. We applied best practices in data sharing to report the results of a study...
One expectation of community-based participatory research (CBPR) is participant access to study results. However, reporting experimental data produced by studies involving biological measurements in the absence of clinical relevance can be challenging to scientists and participants. We applied best practices in data sharing to report the results of a study...
One expectation of community-based participatory research (CBPR) is participant access to study results. However, reporting experimental data produced by studies involving biological measurements in the absence of clinical relevance can be challenging to scientists and participants. We applied best practices in data sharing to report the results of a study...
Few studies have been published on the excretion rates of parent polycyclic aromatic hydrocarbons (PAHs) and hydroxy-polycyclic aromatic hydrocarbons (OH-PAHs) following oral exposure. This study investigated metabolism and excretion rates of 4 parent PAHs and 10 OH-PAHs after the consumption of smoked salmon. Nine members of the Confederated Tribes of...
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in Native Americans
Oleksii Motorykin1, Lisandra Santiago-Delgado1, Diana Rholman2, Jill E
Few studies have been published on the excretion rates of parent polycyclic aromatic hydrocarbons (PAHs) and hydroxy-polycyclic aromatic hydrocarbons (OH-PAHs) following oral exposure. This study investigated metabolism and excretion rates of 4 parent PAHs and 10 OH-PAHs after the consumption of smoked salmon. Nine members of the Confederated Tribes of...
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Collected after Consumption of Traditionally Smoked Salmon for Native
American Volunteers
Motorykin, O
A method was developed for the measurement of 19 parent PAHs (PAHs) and 34 hydroxylated
PAHs (OH-PAHs) in urine and personal air samples of particulate matter less than 2.5 um in
diameter (PM[subscript 2.5]) using GC-MS and validated using NIST SRM 3672 (Organic Contaminants in
Smoker’s Urine) and SRM 3673...
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[subscript
2.5] and Urine Samples Collected During Native American Fish
Smoking Activities
Motorykin, O
A method was developed for the measurement of 19 parent PAHs (PAHs) and 34 hydroxylated
PAHs (OH-PAHs) in urine and personal air samples of particulate matter less than 2.5 um in
diameter (PM[subscript 2.5]) using GC-MS and validated using NIST SRM 3672 (Organic Contaminants in
Smoker’s Urine) and SRM 3673...
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Activities
Oleksii Motorykin1, Jill Schrlau2, Yuling Jia2, Barbara Harper3, Stuart Harris3, Anna Harding4