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Filtering by: Subject Oligonucleotides -- Synthesis

Solid-phase synthesis and biophysical testing of uncharged acyclic oligonucleotide analogues

Creator:

Nelson, Jeffrey Stephen, 1962-

Resource Type:

Dissertation

Full Text:

and Biophysical Testing of Uncharged Acyclic Oligonucleotide Analogues. Abstract approved: Dwight D
Advances in solid phase synthesis of neutral oligonucleotide analogues

Creator:

Wang, Haiyan, 1963-

Abstract:

A novel acyl protecting group for cytosine and adenine has been prepared from 4-( chloromethyl) benzoic acid. Reaction of the acid with morpholine produces 4-( 4-morpholinyl )methyl benzoic acid which is converted to it's acid chloride with thionyl chloride. This may be used to acylate cytidine and adenosine under standard...

Resource Type:

Masters Thesis

Full Text:

oligonucleotide analogues AN ABSTRACT OF THE THESIS OF Haiyan Wang for the degree of Master of Science in