Index Catalog // ScholarsArchive@OSU

Enhanced Protein Homeostasis Mechanisms in Naked Mole Rats Cells

Creator:: Pride, Harrison, Coles, Alex, Mochnick, Jillian, Zhang, Yiqiang, Buffenstein, Rochelle, Hornsby, Peter J., Austad, Steve, Richardson, Arlan, and Perez, Viviana I.
Abstract:: Phylogenic studies suggest that cells from long-lived species are more resistant to a variety of stressors than short-lived species. However, there is little information on the cellular mechanisms that give rise to increased resistance to stress. Our previous studies have shown that liver proteins from a long-lived species have lower...
Resource Type:: Poster

The Role of Nrf2 in Brain Cellular Senescence

Creator:: Ross, Grace K.
Abstract:: Aging is a major risk factor for the deterioration of biochemical pathways that lead to many chronic neurodegenerative disorders (i.e. Parkinson’s and Alzheimer's Disease). Cellular senescence is a hallmark of aging, a condition characterized by stable growth arrest resulting in a cell that no longer divides, but is metabolically active....
Resource Type:: Honors College Thesis
Full Text:: :_____________________________________________________ Viviana Perez Aging is a major risk factor for the deterioration of biochemical pathways

Identifying the role of autophagy in the protection against protein aggregation

Creator:: Chung, Ryan H
Abstract:: Aging is a process that all living species experiences and it also is greatly to study and understand the aging process with the aim of extending human life span. Protein homeostasis is one of the main hall mark of aging. Based on previous data, it observed that cells from long...
Resource Type:: Poster
Full Text:: Discussion and Future Direction Chung, R.1, Sunchu B.1,2, and Perez, V.I.1,2 Figure 1. The graph above

The Effects of Rapamycin on the Unfolded Protein Response in Relation to Healthy Aging

Creator:: Zhao, Stephanie Anne
Abstract:: The loss of proteostasis is the mechanism for maintaining properly folded proteins and degrading misfolded ones. One protective mechanism against loss of proteostasis is the Unfolded Protein Response (UPR), a chaperone mediated folding system in the Endoplasmic Reticulum (ER). The UPR communicates with the Nrf2 pathway, a transcription factor, and...
Resource Type:: Honors College Thesis
Full Text:: Dr. Viviana Perez for giving me the wonderful opportunity to work in her lab. I have been able to

Comparing 26S Proteasome Efficiency Between Long-Living and Short-Living Rodents

Creator:: Bradley, Lynda M.
Abstract:: Many people die yearly worldwide due to diseases associated with aging, and if the process of aging in humans was more understood, the health of these patients could be improved. While many biochemical actions are involved with the aging process, loss of proteostasis has been called one of the most...
Resource Type:: Honors College Thesis
Full Text:: Abstract approved: ______________________________________________________ Viviana Pérez Many

Comparative analysis of genes regulating HDL function and metabolism in macaques and humans

Creator:: Clarke, Jordyn M.
Abstract:: The role of the high density lipoprotein (HDL) molecule is currently an area of great interest within the scientific community. Previously, mouse and human studies have demonstrated an inverse association between HDL cholesterol (HDL-C) levels and cardiovascular disease. Recent clinical trials, which increased HDL-C, have failed to reduce the number...
Resource Type:: Honors College Thesis
Full Text:: :_____________________________________________________ Viviana Perez The role of the high density lipoprotein (HDL) molecule is currently an area of

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Creator:: Riordan, Ruben
Abstract:: Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting nearly 44 million individuals worldwide, yet there are not currently any effective treatments or preventions for AD despite the rapid development in our understanding of the disease over the last four decades. The medical and sanitary innovations of the last century...
Resource Type:: Dissertation
Full Text:: Viviana I. Perez Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting

Characterizing the accumulation of cellular senescence in the PS19 mouse model

Creator:: Valerio, Juno, Riordan, Ruben, Dimas-Munoz, Jovita, Ross, Grace, Zhen, Yu, Wang, Rong, and Perez, Viviana
Abstract:: Research poster for Summer Undergraduate Research Symposium 2019. Research was conducted with CURE funding in the Perez lab studying cellular senescence in the PS19 mouse model.
Resource Type:: Poster
Full Text:: , Jovita Dimas-Munoz, Grace Ross, Yu Zhen, Rong Wang, Viviana Perez Biochemistry and Biophysics - College

The role of Nrf2 in the anti-cell senescence effect of rapamycin

Creator:: Dang, Ivana N.
Resource Type:: Presentation
Full Text:: & Biophysics Dr. Viviana Perez Aging  Aging is a universal process  Lifespan has increased but with

Perez-Perez 0163.pdf

Creator:: Pérez-Pérez, Marcos, Garza-Gil, Dolores, Varela-Lafuente, Manuel, and Surís-Regueiro, Juan
Abstract:: The aim of this work is to develop a predator-prey model for two species of commercial importance captured by the European fishing fleet in the European Grounds. In this model, the hake (Merluccius merluccius) represents the predator, and the blue whiting (Micromesistius poutassou) is the prey. Both the predator and...
Full Text:: BLUE WHITING SPANISH FISHERIES Pérez-Pérez, Marcos1; Garza-Gil, M. Dolores2; Varela-Lafuente

ScholarsArchive@OSU

Enhanced Protein Homeostasis Mechanisms in Naked Mole Rats Cells

The Role of Nrf2 in Brain Cellular Senescence

Identifying the role of autophagy in the protection against protein aggregation

The Effects of Rapamycin on the Unfolded Protein Response in Relation to Healthy Aging

Comparing 26S Proteasome Efficiency Between Long-Living and Short-Living Rodents

Comparative analysis of genes regulating HDL function and metabolism in macaques and humans

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Characterizing the accumulation of cellular senescence in the PS19 mouse model

The role of Nrf2 in the anti-cell senescence effect of rapamycin

Perez-Perez 0163.pdf

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Conference Name

Conference Section/Track

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Location

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search