The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic
prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well
tolerated at pharmacological doses. However, the underlying mechanism(s) responsible for cancer suppression remain to be...
Full Text:
-Sanchez, Z., Black, C., Maier, C.
S., Williams, D. E., ... & Ho, E. (2014). SUV39H1/H3K9me3 attenuates
The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic
prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well
tolerated at pharmacological doses. However, the underlying mechanism(s) responsible for cancer suppression remain to be...
The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic
prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well
tolerated at pharmacological doses. However, the underlying mechanism(s) responsible for cancer suppression remain to be...
There is a significant need for technological advancement in blood processing. New technologies in rapid processing of frozen blood products could significantly improve management of the blood supply chain in the United States by enabling on-demand use of frozen blood products that can be stored for 10 years instead of...
Epigenetic changes, including aberrant DNA methylation, result in altered gene expression and play an important role in
carcinogenesis. Phytochemicals such as sulforaphane (SFN) and 3,3'-diindolylmethane (DIM) are promising chemopreventive
agents for the treatment of prostate cancer. Both have been shown to induce re-expression of genes, including tumor
suppressor genes silenced...
Full Text:
, Palomera-SanchezZ, Beaver LM, et al. (2014)
Effects of Sulforaphane and 3,3'-Diindolylmethane on Genome
Shear wave velocity is a fundamental property of a granular assembly. It is a measure of the true elastic stiffness of a bulk specimen of discrete grains. Shear wave velocity is typically measured in the laboratory (e.g., using bender elements) or in-situ (e.g., using a seismic cone penetrometer, sCPT). In...
Juniper (Juniperus spp.) encroachment into the sagebrush steppe ecoregion is one of the main causes of sagebrush degradation and can alter the understory vegetative community by outcompeting native shrubs and grasses, which reduces the available forage and cover for small mammals. Coyotes (Canis latrans) are generalist, omnivorous predators in the...
The purpose of this study was to describe the leadership development process
of former student leaders at Snow College. More specifically, the study focused on
understanding how, when, and where leadership development took place in their
"lived experience" within the student government at Snow College (Van Manen,
1998). Examining the...
Community colleges in the United States have become an important educational destination for international students. According to the Institute of International Education (IIE, 2006), international students who enrolled for the first time at a U.S. campus increased by 8 per cent, from 131,946 students in 2004/2005 to 142,923 in 2005/2006....
The research‘s purpose was to examine how exemplary community college study abroad programs assisted student participants in acquiring global competence. Three research questions were explored: 1.What issues need to be anticipated when planning a study abroad program for community college students in order to effectively incorporate opportunities for students to...