Dysregulation of Sonic hedgehog (Shh) signaling has been implicated in glioma pathogenesis. Yet, the role of this pathway in gliomagenesis remains controversial because of the lack of relevant animal models. Using the cytokeratin 5 promoter, we ectopically expressed a constitutively active zebrafish Smoothened (Smoa1) in neural progenitor cells and analyzed...
The Internet of Things (IoT) paradigm brought an ever-increasing dependence on low-power devices to collect sensor data and transmit that information to the cloud, placing greater demand on connectivity and lifespan. In response, rapid worldwide innovation demonstrates the trade-offs in processing, communication, and energy consumption with diverse approaches to low-power...