Polymorphonuclear leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal concentrations of reactive oxygen species (ROS) due to mutations in NOX2. Patients with CGD suffer from severe, life-threatening infections and inflammatory complications. Granulibacter bethesdensis is an emerging Gram-negative pathogen in CGD that resists killing by PMN...
The fishing communities in the St. Anthony area of Newfoundland, Canada, were forced to adjust to the
collapse of cod catches in Atlantic Canada in the early 1990’s. It was not only the fishing industry that
was affected. The entire community had to live through the changes in resources. To...
Great blue heron (Ardea herodias) eggs and prey items were collected from six colonies on the Columbia and Willamette rivers and Puget Sound during 1994-95. Contaminant concentrations, reproductive success, and biomagnification factors (BMFs) were determined and effects of residue levels were measured by H4IIE rat hepatoma and ethoxyresorufin-O-dealkylase (EROD) bioassays....
The purpose of this study was to examine the total direct costs of occupational injuries as they relate to workers compensation allocations within a self-insured firm.
Through the use of a model, this study provides financial impact information for safety professionals by defining the total direct costs of occupational injuries....
Lead is a ubiquitous environmental toxin known to cause neurological deficits in children. There is no biological need for lead and no safe level of lead in the body has ever been identified. Despite dramatic decline in mean blood lead levels nationwide since the U.S. EPA’s ban on lead-based paint...
Combustion emissions produced from burning real transportation fuels have many environmental impacts. However, detailed chemistry across multiple phases, time scales, and thermodynamic conditions make predicting combustion emissions challenging. Detailed modeling of the gas phase alone is prohibitively expensive, due to the large size and stiffness of the kinetic models. The...
Exercise training has consistently been shown to increase fat utilization during exercise, while conflicting results have been reported on the effects of sex and age on fuel metabolism during exercise. PURPOSE: The primary objective of this investigation was to compare fat and carbohydrate utilization during exercise among males and females...
Identifying habitat and spatial requirements of wildlife species across multiple spatial scales is a challenging, yet crucial component of wildlife management. Habitat use of bats is particularly difficult to study, and managing habitat to conserve bats is especially challenging because bats are highly vagile organisms that exploit several different types...
The vascular endothelium is a single cell layer that lines the lumen of the entire vasculature. It is the site of synthesis of nitric oxide (NO), a vasodilatory compound synthesized by endothelial nitric oxide synthase (eNOS). NO causes intracellular calcium sequestration of the vascular smooth muscle cells, relaxing and dilating...
The object of this study was to investigate the possibilities
of tracing aggregational behavior among Bufo boreas boreas
larvae with reference to tadpole development, and to attempt to determine
what aggregational factors initiate and maintain this behavior.
Additionally, an attempt was made to determine the significance
of temperature as an...