Achlys triphylla, a member of a medicinally active family
containing alkaloids, was examined phytochemically to determine its
possible value as a source of medicinal agents.
Pharmacological testing of the crude ethanol extract exhibited
a competitive inhibition of acetylcholine and histamine. Purification
of alkaloid 'A' from the crude ethanol extract and...
This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Coibamide A is a highly methylated cyclic depsipeptide isolated from Panamanian marine filamentous cyanobacteria as part of an International Cooperative Biodiversity Groups (ICBG) program based in Panama. This structurally unique agent exhibits potent cancer cell toxicity with an unprecedented selectivity profile in the National Cancer Institute (NCI) 60 cell line...